Entry Database : PDB / ID : 6tzz Structure visualization Downloads & linksTitle Crystal Structure of Tetrahymena Thermophila Lipin Phosphatidic Acid Phosphatase with Magnesium ComponentsNuclear elongation and deformation protein Details Keywords HYDROLASE / Lipin / phosphatidic acid phosphatase / immunoglobulin-like / haloacid dehalogenaseFunction / homology Function and homology informationFunction Domain/homology Component
phosphatidate phosphatase activity / triglyceride biosynthetic process / fatty acid catabolic process / cellular response to insulin stimulus / transcription coactivator activity / positive regulation of transcription by RNA polymerase II / nucleus / metal ion binding Similarity search - Function Lipin, N-terminal / Lipin/Ned1/Smp2 (LNS2) / LIPIN family / LNS2/PITP / lipin, N-terminal conserved region / LNS2 (Lipin/Ned1/Smp2) / LNS2 / HAD superfamily / HAD-like superfamily Similarity search - Domain/homologyBiological species Tetrahymena thermophila (eukaryote)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / SAD / molecular replacement / Resolution : 3 Å DetailsAuthors Khayyo, V.I. / Airola, M.V. Funding support United States, 3items Details Hide detailsOrganization Grant number Country National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) R35GM128666 United States American Heart Association 17SDG33410860 United States American Heart Association 19PRE34450192 United States
CitationJournal : Nat Commun / Year : 2020Title : Crystal structure of a lipin/Pah phosphatidic acid phosphataseAuthors : Khayyo, V.I. / Hoffmann, R.M. / Wang, H. / Bell, J.A. / Burke, J.E. / Reue, K. / Airola, M.V. History Deposition Aug 13, 2019 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Mar 18, 2020 Provider : repository / Type : Initial releaseRevision 1.1 Mar 13, 2024 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / struct_conn / struct_ncs_dom_lim Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id
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