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- PDB-6ta7: CRYSTAL STRUCTURE OF HUMAN G3BP1-NTF2 IN COMPLEX WITH HUMAN CAPRI... -
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Basic information
Entry | Database: PDB / ID: 6ta7 | ||||||
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Title | CRYSTAL STRUCTURE OF HUMAN G3BP1-NTF2 IN COMPLEX WITH HUMAN CAPRIN1-DERIVED SOLOMON MOTIF | ||||||
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![]() | RNA BINDING PROTEIN / Stress Granule / Complex / Regulation / Low Complexity Regions / Phase Transition | ||||||
Function / homology | ![]() regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA / DNA/RNA helicase activity / positive regulation of stress granule assembly / intracellular mRNA localization / positive regulation of dendritic spine morphogenesis / non-membrane-bounded organelle assembly / positive regulation of dendrite morphogenesis / intracellular non-membrane-bounded organelle / generation of neurons / cell leading edge ...regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA / DNA/RNA helicase activity / positive regulation of stress granule assembly / intracellular mRNA localization / positive regulation of dendritic spine morphogenesis / non-membrane-bounded organelle assembly / positive regulation of dendrite morphogenesis / intracellular non-membrane-bounded organelle / generation of neurons / cell leading edge / ribosomal small subunit binding / positive regulation of type I interferon production / signaling adaptor activity / stress granule assembly / DNA helicase activity / synapse assembly / molecular condensate scaffold activity / molecular function activator activity / P-body / negative regulation of canonical Wnt signaling pathway / cytoplasmic stress granule / lamellipodium / perikaryon / endonuclease activity / defense response to virus / DNA helicase / Ras protein signal transduction / RNA helicase activity / negative regulation of translation / RNA helicase / ribonucleoprotein complex / innate immune response / focal adhesion / mRNA binding / synapse / dendrite / SARS-CoV-2 activates/modulates innate and adaptive immune responses / ATP hydrolysis activity / DNA binding / RNA binding / ATP binding / membrane / nucleus / cytoplasm / cytosol Similarity search - Function | ||||||
Biological species | ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Schulte, T. / Achour, A. / Panas, M.D. / McInerney, G.M. | ||||||
![]() | ![]() Title: Caprin-1 binding to the critical stress granule protein G3BP1 is regulated by pH Authors: Schulte, T. / Panas, M.D. / Williams, L. / Kedersha, N. / Fleck, J.S. / Tan, T.J. / Olsson, A. / Morro, A.M. / Hanke, L. / Nilvebrant, J. / Giang, K.A. / Nygren, P.A. / Anderson, P. / ...Authors: Schulte, T. / Panas, M.D. / Williams, L. / Kedersha, N. / Fleck, J.S. / Tan, T.J. / Olsson, A. / Morro, A.M. / Hanke, L. / Nilvebrant, J. / Giang, K.A. / Nygren, P.A. / Anderson, P. / Achour, A. / McInerney, G.M. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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PDBx/mmCIF format | ![]() | 479.1 KB | Display | ![]() |
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PDB format | ![]() | 383.2 KB | Display | ![]() |
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-Validation report
Summary document | ![]() | 479.3 KB | Display | ![]() |
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Full document | ![]() | 486.2 KB | Display | |
Data in XML | ![]() | 32 KB | Display | |
Data in CIF | ![]() | 44.9 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 5fw5S S: Starting model for refinement |
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Similar structure data |
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Assembly
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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