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- PDB-6slo: Crystal structure of PUF60 UHM domain in complex with 7,8 dimetho... -
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Open data
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Basic information
Entry | Database: PDB / ID: 6slo | ||||||
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Title | Crystal structure of PUF60 UHM domain in complex with 7,8 dimethoxyperphenazine | ||||||
![]() | Thioredoxin,Poly(U)-binding-splicing factor PUF60 | ||||||
![]() | SPLICING / UHM domain / Splicing Inhibitor | ||||||
Function / homology | ![]() glycerol ether metabolic process / alternative mRNA splicing, via spliceosome / mRNA splice site recognition / precatalytic spliceosome / regulation of alternative mRNA splicing, via spliceosome / protein-disulfide reductase activity / catalytic step 2 spliceosome / mRNA Splicing - Major Pathway / cell junction / cadherin binding ...glycerol ether metabolic process / alternative mRNA splicing, via spliceosome / mRNA splice site recognition / precatalytic spliceosome / regulation of alternative mRNA splicing, via spliceosome / protein-disulfide reductase activity / catalytic step 2 spliceosome / mRNA Splicing - Major Pathway / cell junction / cadherin binding / apoptotic process / DNA binding / RNA binding / nucleoplasm / identical protein binding Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Jagtap, P.K.A. / Kubelka, T. / Bach, T. / Sattler, M. | ||||||
![]() | ![]() Title: Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly. Authors: Jagtap, P.K.A. / Kubelka, T. / Soni, K. / Will, C.L. / Garg, D. / Sippel, C. / Kapp, T.G. / Potukuchi, H.K. / Schorpp, K. / Hadian, K. / Kessler, H. / Luhrmann, R. / Hausch, F. / Bach, T. / Sattler, M. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 357.5 KB | Display | ![]() |
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PDB format | ![]() | 290.3 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 1013.8 KB | Display | ![]() |
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Full document | ![]() | 1 MB | Display | |
Data in XML | ![]() | 39.6 KB | Display | |
Data in CIF | ![]() | 57.4 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 3dxbS S: Starting model for refinement |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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Unit cell |
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Components on special symmetry positions |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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