登録情報 | データベース: PDB / ID: 6ska |
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タイトル | Teneurin 2 in complex with Latrophilin 1 Lec-Olf domains |
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要素 | - Adhesion G protein-coupled receptor L1
- Teneurin-2
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キーワード | SIGNALING PROTEIN / adhesion / Odz / Lphn / synapse / neurons / repulsion / olfactomedin / lectin / YD-repeat / complex |
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機能・相同性 | 機能・相同性情報
latrotoxin receptor activity / positive regulation of synapse maturation / positive regulation of synapse assembly / positive regulation of filopodium assembly / heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules / : / toxic substance binding / neuron development / cell adhesion molecule binding / filopodium ...latrotoxin receptor activity / positive regulation of synapse maturation / positive regulation of synapse assembly / positive regulation of filopodium assembly / heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules / : / toxic substance binding / neuron development / cell adhesion molecule binding / filopodium / G protein-coupled receptor activity / axon guidance / adenylate cyclase-activating G protein-coupled receptor signaling pathway / PML body / cell-cell adhesion / cell-cell junction / cell junction / presynaptic membrane / growth cone / carbohydrate binding / postsynaptic membrane / dendritic spine / cell surface receptor signaling pathway / neuron projection / protein heterodimerization activity / axon / signaling receptor binding / glutamatergic synapse / synapse / calcium ion binding / dendrite / Golgi apparatus / negative regulation of transcription by RNA polymerase II / endoplasmic reticulum / protein homodimerization activity / nucleus / plasma membrane類似検索 - 分子機能 Latrophilin-1 / Rhamnose-binding lectin domain (RBL) / Teneurin intracellular, N-terminal / Teneurin Intracellular Region / Teneurin N-terminal domain profile. / Tox-GHH domain / GHH signature containing HNH/Endo VII superfamily nuclease toxin / GPCR, family 2, latrophilin, C-terminal / GPCR, family 2, latrophilin / Latrophilin Cytoplasmic C-terminal region ...Latrophilin-1 / Rhamnose-binding lectin domain (RBL) / Teneurin intracellular, N-terminal / Teneurin Intracellular Region / Teneurin N-terminal domain profile. / Tox-GHH domain / GHH signature containing HNH/Endo VII superfamily nuclease toxin / GPCR, family 2, latrophilin, C-terminal / GPCR, family 2, latrophilin / Latrophilin Cytoplasmic C-terminal region / D-galactoside/L-rhamnose binding SUEL lectin domain superfamily / GAIN domain, N-terminal / GPCR-Autoproteolysis INducing (GAIN) domain / D-galactoside/L-rhamnose binding SUEL lectin domain / Galactose binding lectin domain / SUEL-type lectin domain profile. / YD repeat / Olfactomedin-like domain / Olfactomedin-like domain / Olfactomedin-like domain profile. / Olfactomedin-like domains / Rhs repeat-associated core / Carboxypeptidase-like, regulatory domain superfamily / GAIN domain superfamily / GPCR proteolysis site, GPS, motif / GPS motif / GAIN-B domain profile. / G-protein-coupled receptor proteolytic site domain / Hormone receptor domain / GPCR, family 2, extracellular hormone receptor domain / G-protein coupled receptors family 2 profile 1. / Domain present in hormone receptors / GPCR family 2, extracellular hormone receptor domain superfamily / G-protein coupled receptors family 2 signature 2. / GPCR, family 2, secretin-like, conserved site / Six-bladed beta-propeller, TolB-like / GPCR, family 2, secretin-like / 7 transmembrane receptor (Secretin family) / Quinoprotein alcohol dehydrogenase-like superfamily / GPCR, family 2-like / G-protein coupled receptors family 2 profile 2. / EGF-like calcium-binding domain / Calcium-binding EGF-like domain / Epidermal growth factor-like domain. / EGF-like domain profile. / EGF-like domain signature 2. / EGF-like domain signature 1. / EGF-like domain / Jelly Rolls / Sandwich / Mainly Beta類似検索 - ドメイン・相同性 Adhesion G protein-coupled receptor L1 / Teneurin-2類似検索 - 構成要素 |
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生物種 | ![](img/tx_bird.gif) Gallus gallus (ニワトリ)
![](img/tx_mammal.gif) Mus musculus (ハツカネズミ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 3.86 Å |
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データ登録者 | Chu, A. / Carrasquero, M.A. / Lowe, E. / Seiradake, E. |
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資金援助 | 英国, 1件 組織 | 認可番号 | 国 |
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Wellcome Trust | | 英国 |
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引用 | ジャーナル: Cell / 年: 2020 タイトル: Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons. 著者: Del Toro, D. / Carrasquero-Ordaz, M.A. / Chu, A. / Ruff, T. / Shahin, M. / Jackson, V.A. / Chavent, M. / Berbeira-Santana, M. / Seyit-Bremer, G. / Brignani, S. / Kaufmann, R. / Lowe, E. / ...著者: Del Toro, D. / Carrasquero-Ordaz, M.A. / Chu, A. / Ruff, T. / Shahin, M. / Jackson, V.A. / Chavent, M. / Berbeira-Santana, M. / Seyit-Bremer, G. / Brignani, S. / Kaufmann, R. / Lowe, E. / Klein, R. / Seiradake, E. |
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履歴 | 登録 | 2019年8月15日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2020年2月12日 | Provider: repository / タイプ: Initial release |
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改定 2.0 | 2020年7月29日 | Group: Atomic model / Data collection ...Atomic model / Data collection / Derived calculations / Structure summary カテゴリ: atom_site / atom_site_anisotrop ...atom_site / atom_site_anisotrop / chem_comp / entity / pdbx_branch_scheme / pdbx_chem_comp_identifier / pdbx_entity_branch / pdbx_entity_branch_descriptor / pdbx_entity_branch_link / pdbx_entity_branch_list / pdbx_entity_nonpoly / pdbx_nonpoly_scheme / pdbx_struct_assembly_gen / pdbx_struct_conn_angle / struct_asym / struct_conn / struct_site / struct_site_gen Item: _atom_site.B_iso_or_equiv / _atom_site.Cartn_x ..._atom_site.B_iso_or_equiv / _atom_site.Cartn_x / _atom_site.Cartn_y / _atom_site.Cartn_z / _atom_site.auth_asym_id / _atom_site.auth_atom_id / _atom_site.auth_comp_id / _atom_site.auth_seq_id / _atom_site.label_asym_id / _atom_site.label_atom_id / _atom_site.label_comp_id / _atom_site.label_entity_id / _atom_site.type_symbol / _atom_site_anisotrop.U[1][1] / _atom_site_anisotrop.U[1][2] / _atom_site_anisotrop.U[1][3] / _atom_site_anisotrop.U[2][2] / _atom_site_anisotrop.U[2][3] / _atom_site_anisotrop.U[3][3] / _atom_site_anisotrop.pdbx_auth_asym_id / _atom_site_anisotrop.pdbx_auth_atom_id / _atom_site_anisotrop.pdbx_auth_comp_id / _atom_site_anisotrop.pdbx_auth_seq_id / _atom_site_anisotrop.pdbx_label_asym_id / _atom_site_anisotrop.pdbx_label_atom_id / _atom_site_anisotrop.pdbx_label_comp_id / _atom_site_anisotrop.type_symbol / _chem_comp.name / _entity.formula_weight / _entity.pdbx_description / _entity.pdbx_number_of_molecules / _entity.type / _pdbx_struct_assembly_gen.asym_id_list / _pdbx_struct_conn_angle.ptnr2_label_asym_id / _struct_conn.conn_type_id / _struct_conn.id / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.pdbx_role / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id 解説: Carbohydrate remediation / Provider: repository / タイプ: Remediation |
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