登録情報 | データベース: PDB / ID: 6sh7 |
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タイトル | Crystal structure of the human DEAH-helicase DHX15 in complex with the NKRF G-patch |
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要素 | - NF-kappa-B-repressing factor
- Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15
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キーワード | HYDROLASE / G-patch / DEAH helicase / DExH helicase |
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機能・相同性 | 機能・相同性情報
U12-type spliceosomal complex / ATP-dependent activity, acting on RNA / response to alkaloid / antiviral innate immune response / ATPase activator activity / mRNA Splicing - Major Pathway / RNA splicing / helicase activity / spliceosomal complex / response to toxic substance ...U12-type spliceosomal complex / ATP-dependent activity, acting on RNA / response to alkaloid / antiviral innate immune response / ATPase activator activity / mRNA Splicing - Major Pathway / RNA splicing / helicase activity / spliceosomal complex / response to toxic substance / mRNA processing / mRNA splicing, via spliceosome / double-stranded RNA binding / DNA-binding transcription activator activity, RNA polymerase II-specific / positive regulation of canonical NF-kappaB signal transduction / defense response to virus / RNA helicase activity / RNA helicase / nuclear speck / defense response to bacterium / RNA polymerase II cis-regulatory region sequence-specific DNA binding / negative regulation of DNA-templated transcription / nucleolus / ATP hydrolysis activity / positive regulation of transcription by RNA polymerase II / RNA binding / nucleoplasm / ATP binding / nucleus類似検索 - 分子機能 NF-kappaB-repression factor, R3H domain / Putative single-stranded nucleic acids-binding domain / DHX15, DEXH-box helicase domain / R3H domain / R3H domain / R3H domain superfamily / R3H domain profile. / G-patch domain / G-patch domain profile. / G-patch domain ...NF-kappaB-repression factor, R3H domain / Putative single-stranded nucleic acids-binding domain / DHX15, DEXH-box helicase domain / R3H domain / R3H domain / R3H domain superfamily / R3H domain profile. / G-patch domain / G-patch domain profile. / G-patch domain / glycine rich nucleic binding domain / : / Helicase associated domain (HA2), ratchet-like / DEAD-box helicase, OB fold / Oligonucleotide/oligosaccharide-binding (OB)-fold / Helicase-associated domain / Helicase associated domain (HA2), winged-helix / Helicase associated domain (HA2) Add an annotation / Double-stranded RNA binding motif / DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site / DEAH-box subfamily ATP-dependent helicases signature. / Double-stranded RNA-binding domain / DEAD/DEAH box helicase / DEAD/DEAH box helicase domain / Helicase conserved C-terminal domain / helicase superfamily c-terminal domain / Superfamilies 1 and 2 helicase C-terminal domain profile. / Superfamilies 1 and 2 helicase ATP-binding type-1 domain profile. / DEAD-like helicases superfamily / Helicase, C-terminal / Helicase superfamily 1/2, ATP-binding domain / P-loop containing nucleoside triphosphate hydrolase類似検索 - ドメイン・相同性 NF-kappa-B-repressing factor / ATP-dependent RNA helicase DHX15類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.21 Å |
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データ登録者 | Jonas, S. / Studer, M.K. / Ivanovic, L. |
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資金援助 | スイス, 2件 組織 | 認可番号 | 国 |
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Swiss National Science Foundation | 31003A_179498 | スイス | Swiss National Science Foundation | 182880 | スイス |
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引用 | #1: ジャーナル: Acta Crystallogr. D Biol. Crystallogr. / 年: 2012タイトル: Towards automated crystallographic structure refinement with phenix.refine. 著者: Afonine, P.V. / Grosse-Kunstleve, R.W. / Echols, N. / Headd, J.J. / Moriarty, N.W. / Mustyakimov, M. / Terwilliger, T.C. / Urzhumtsev, A. / Zwart, P.H. / Adams, P.D. |
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履歴 | 登録 | 2019年8月5日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2020年4月22日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2024年1月24日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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