- PDB-6p1o: Post-catalytic nicked complex of human DNA Polymerase Mu with 1-n... -
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基本情報
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データベース: PDB / ID: 6p1o
タイトル
Post-catalytic nicked complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and newly incorporated dAMP
要素
DNA (5'-D(*CP*GP*GP*CP*(8OG)P*TP*AP*CP*G)-3')
DNA (5'-D(*CP*GP*TP*AP*A)-3')
DNA (5'-D(P*GP*CP*CP*G)-3')
DNA-directed DNA/RNA polymerase mu
キーワード
TRANSFERASE / Family X polymerase / NHEJ
機能・相同性
機能・相同性情報
Nonhomologous End-Joining (NHEJ) / double-strand break repair via nonhomologous end joining / DNA recombination / DNA-directed DNA polymerase / DNA-directed DNA polymerase activity / DNA binding / nucleoplasm / nucleus / metal ion binding 類似検索 - 分子機能
DNA-directed DNA/RNA polymerase mu / DNA nucleotidylexotransferase (TdT) / DNA-directed DNA/RNA polymerase mu / Beta Polymerase; domain 3 / DNA polymerase, thumb domain / DNA polymerase beta, N-terminal domain-like / DNA polymerase beta, palm domain / DNA polymerase beta palm / DNA polymerase lambda, fingers domain / Fingers domain of DNA polymerase lambda / DNA-directed DNA polymerase X ...DNA-directed DNA/RNA polymerase mu / DNA nucleotidylexotransferase (TdT) / DNA-directed DNA/RNA polymerase mu / Beta Polymerase; domain 3 / DNA polymerase, thumb domain / DNA polymerase beta, N-terminal domain-like / DNA polymerase beta, palm domain / DNA polymerase beta palm / DNA polymerase lambda, fingers domain / Fingers domain of DNA polymerase lambda / DNA-directed DNA polymerase X / DNA polymerase beta-like, N-terminal domain / Helix-hairpin-helix domain / DNA polymerase X family / DNA polymerase family X, binding site / DNA polymerase family X signature. / DNA polymerase lambda lyase domain superfamily / DNA polymerase family X / DNA polymerase beta, thumb domain / DNA polymerase beta thumb / DNA polymerase, thumb domain superfamily / Beta Polymerase, domain 2 / Beta Polymerase; domain 2 / BRCT domain profile. / BRCT domain / BRCT domain superfamily / Nucleotidyltransferase superfamily / 5' to 3' exonuclease, C-terminal subdomain / DNA polymerase; domain 1 / 2-Layer Sandwich / Orthogonal Bundle / Mainly Alpha / Alpha Beta 類似検索 - ドメイン・相同性
ADENOSINE-5'-TRIPHOSPHATE / : / PYROPHOSPHATE / DNA / DNA-directed DNA/RNA polymerase mu 類似検索 - 構成要素
#241 - 2020年1月 20年の分子を振り返って (Twenty Years of Molecules) 類似性 (1)
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集合体
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A: DNA-directed DNA/RNA polymerase mu T: DNA (5'-D(*CP*GP*GP*CP*(8OG)P*TP*AP*CP*G)-3') P: DNA (5'-D(*CP*GP*TP*AP*A)-3') D: DNA (5'-D(P*GP*CP*CP*G)-3') ヘテロ分子
The authors state that anomalous signal is observed for the metal A site (peak greater than 10 ...The authors state that anomalous signal is observed for the metal A site (peak greater than 10 sigma), though no anomalous scatterers were added to the crystallization or soaking solutions. Therefore, this metal has been modeled as manganese, based on the coordination geometry and interatomic distances.