Entry Database : PDB / ID : 6oca Structure visualization Downloads & linksTitle Ricin A chain bound to VHH antibody V2G10 ComponentsRicin A chain VHH antibody V2G10 DetailsKeywords TOXINFunction / homology Function and homology informationFunction Domain/homology Component
rRNA N-glycosylase / rRNA N-glycosylase activity / AMP binding / defense response / carbohydrate binding / toxin activity / killing of cells of another organism / negative regulation of translation Similarity search - Function Ricin (A Subunit), domain 2 / Ricin (A Subunit), domain 2 / Ricin (A subunit); domain 1 / Ricin (A subunit), domain 1 / Ribosome-inactivating protein conserved site / Shiga/ricin ribosomal inactivating toxins active site signature. / Ricin-type beta-trefoil lectin domain / Ribosome-inactivating protein type 1/2 / Ribosome-inactivating protein / Ribosome-inactivating protein, subdomain 1 ... Ricin (A Subunit), domain 2 / Ricin (A Subunit), domain 2 / Ricin (A subunit); domain 1 / Ricin (A subunit), domain 1 / Ribosome-inactivating protein conserved site / Shiga/ricin ribosomal inactivating toxins active site signature. / Ricin-type beta-trefoil lectin domain / Ribosome-inactivating protein type 1/2 / Ribosome-inactivating protein / Ribosome-inactivating protein, subdomain 1 / Ribosome-inactivating protein, subdomain 2 / Ribosome-inactivating protein superfamily / Ribosome inactivating protein / Ricin-type beta-trefoil / Lectin domain of ricin B chain profile. / Ricin B, lectin domain / Ricin B-like lectins / Few Secondary Structures / Irregular / 3-Layer(aba) Sandwich / Alpha Beta Similarity search - Domain/homologyBiological species Ricinus communis (castor bean)Vicugna pacos (alpaca)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution : 2.113 Å DetailsAuthors Rudolph, M.J. Funding support United States, 1items Details Hide detailsOrganization Grant number Country National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) HHSN272201400021C United States
CitationJournal : J.Mol.Biol. / Year : 2020Title : Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.Authors : Rudolph, M.J. / Czajka, T.F. / Davis, S.A. / Thi Nguyen, C.M. / Li, X.P. / Tumer, N.E. / Vance, D.J. / Mantis, N.J. History Deposition Mar 22, 2019 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Apr 1, 2020 Provider : repository / Type : Initial releaseRevision 1.1 Oct 14, 2020 Group : Database references / Category : citation / citation_authorItem : _citation.country / _citation.journal_abbrev ... _citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year Revision 1.2 Mar 13, 2024 Group : Data collection / Database references / Category : chem_comp_atom / chem_comp_bond / database_2Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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