- PDB-6ng3: Crystal structure of human CD160 and HVEM complex -
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IDまたはキーワード:
読み込み中...
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基本情報
登録情報
データベース: PDB / ID: 6ng3
タイトル
Crystal structure of human CD160 and HVEM complex
要素
CD160 antigen,Tumor necrosis factor receptor superfamily member 14
キーワード
IMMUNE SYSTEM / CD160 / HVEM / BTLA / gD
機能・相同性
機能・相同性情報
positive regulation of natural killer cell mediated immune response to tumor cell / activating MHC class I receptor activity / negative regulation of CD4-positive, alpha-beta T cell costimulation / positive regulation of natural killer cell degranulation / negative regulation of adaptive immune memory response / negative regulation of alpha-beta T cell proliferation / MHC class I protein complex binding / MHC class Ib receptor activity / positive regulation of natural killer cell cytokine production / mucosal immune response ...positive regulation of natural killer cell mediated immune response to tumor cell / activating MHC class I receptor activity / negative regulation of CD4-positive, alpha-beta T cell costimulation / positive regulation of natural killer cell degranulation / negative regulation of adaptive immune memory response / negative regulation of alpha-beta T cell proliferation / MHC class I protein complex binding / MHC class Ib receptor activity / positive regulation of natural killer cell cytokine production / mucosal immune response / tumor necrosis factor receptor activity / MHC class I receptor activity / TNFs bind their physiological receptors / positive regulation of natural killer cell mediated cytotoxicity / positive regulation of cytokine production involved in immune response / Co-inhibition by BTLA / negative regulation of T cell receptor signaling pathway / cytokine binding / positive regulation of endothelial cell apoptotic process / positive regulation of T cell migration / side of membrane / negative regulation of T cell proliferation / T cell costimulation / negative regulation of angiogenesis / phosphatidylinositol 3-kinase/protein kinase B signal transduction / kinase binding / positive regulation of type II interferon production / Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell / virus receptor activity / angiogenesis / defense response to Gram-negative bacterium / adaptive immune response / cell surface receptor signaling pathway / defense response to Gram-positive bacterium / immune response / receptor ligand activity / signaling receptor binding / innate immune response / external side of plasma membrane / ubiquitin protein ligase binding / extracellular region / plasma membrane 類似検索 - 分子機能
解像度: 2.88→20 Å / Cor.coef. Fo:Fc: 0.924 / Cor.coef. Fo:Fc free: 0.898 / SU B: 18.046 / SU ML: 0.344 / 交差検証法: THROUGHOUT / ESU R: 1.268 / ESU R Free: 0.388 / 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS