登録情報 データベース : PDB / ID : 6jv8 構造の表示 ダウンロードとリンクタイトル Crystal structure of Rat C5a 要素Complement C5 詳細 キーワード IMMUNE SYSTEM / Agonist / C5aR / Immune機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
C5a anaphylatoxin chemotactic receptor binding / : / negative regulation of norepinephrine secretion / membrane attack complex / negative regulation of dopamine secretion / inflammatory response to wounding / cytolysis / leukocyte migration involved in inflammatory response / positive regulation of chemotaxis / negative regulation of macrophage chemotaxis ... C5a anaphylatoxin chemotactic receptor binding / : / negative regulation of norepinephrine secretion / membrane attack complex / negative regulation of dopamine secretion / inflammatory response to wounding / cytolysis / leukocyte migration involved in inflammatory response / positive regulation of chemotaxis / negative regulation of macrophage chemotaxis / glomerulus development / neutrophil homeostasis / complement activation, alternative pathway / complement activation / endopeptidase inhibitor activity / positive regulation of vascular endothelial growth factor production / positive regulation of chemokine production / kidney development / complement activation, classical pathway / intracellular calcium ion homeostasis / positive regulation of angiogenesis / chemotaxis / glucose homeostasis / positive regulation of cytosolic calcium ion concentration / in utero embryonic development / inflammatory response / extracellular space 類似検索 - 分子機能 Complement C5 / Anaphylotoxins (complement system) / Influenza Virus Matrix Protein; Chain A, domain 1 / Complement C3/4/5, macroglobulin domain MG1 / Macroglobulin domain MG1 / Anaphylatoxin domain signature. / Anaphylatoxin, complement system / Anaphylatoxin/fibulin / Anaphylotoxin-like domain / Anaphylatoxin domain profile. ... Complement C5 / Anaphylotoxins (complement system) / Influenza Virus Matrix Protein; Chain A, domain 1 / Complement C3/4/5, macroglobulin domain MG1 / Macroglobulin domain MG1 / Anaphylatoxin domain signature. / Anaphylatoxin, complement system / Anaphylatoxin/fibulin / Anaphylotoxin-like domain / Anaphylatoxin domain profile. / Anaphylatoxin homologous domain / Netrin C-terminal Domain / Netrin module, non-TIMP type / UNC-6/NTR/C345C module / Alpha-macroglobulin, receptor-binding / Alpha-macroglobulin, receptor-binding domain superfamily / Macroglobulin domain MG4 / Macroglobulin domain MG3 / A-macroglobulin receptor binding domain / Macroglobulin domain MG4 / Macroglobulin domain MG3 / A-macroglobulin receptor / Netrin domain / NTR domain profile. / Tissue inhibitor of metalloproteinases-like, OB-fold / Alpha-2-macroglobulin / Macroglobulin domain / Alpha-2-macroglobulin, bait region domain / Alpha-macroglobulin-like, TED domain / Alpha-2-macroglobulin family / MG2 domain / A-macroglobulin TED domain / Alpha-2-macroglobulin bait region domain / Alpha-2-Macroglobulin / Alpha-2-macroglobulin family / Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid / Immunoglobulin-like fold / Up-down Bundle / Mainly Alpha 類似検索 - ドメイン・相同性生物種 Rattus norvegicus (ドブネズミ)手法 X線回折 / 解像度 : 1.582 Å 詳細データ登録者 Zuo, C. 資金援助 中国, 4件 詳細 詳細を隠す組織 認可番号 国 National Natural Science Foundation of China 21532004 中国 National Natural Science Foundation of China 91753205 中国 National Natural Science Foundation of China 81621002 中国 National Natural Science Foundation of China 21621003 中国
引用ジャーナル : To Be Published タイトル : Chimeric protein probes for C5a receptors through fusion of anaphylatoxin C5a core region with a small-molecule antagonist著者 : Zuo, C. 履歴 登録 2019年4月16日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2020年4月22日 Provider : repository / タイプ : Initial release