Entry Database : PDB / ID : 6hzy Structure visualization Downloads & linksTitle Crystal structure of a bacterial fucosidase with inhibitor FucPUG ComponentsAlpha-L-fucosidase Details Keywords HYDROLASEFunction / homology Function and homology informationFunction Domain/homology Component
Alpha-L-fucosidase, metazoa-type / Glycoside hydrolase, family 29 / Alpha-L-fucosidase / Alpha-L-fucosidase / Golgi alpha-mannosidase II / Glycosyl hydrolase, all-beta / Glycosidases / Glycoside hydrolase superfamily / TIM Barrel / Alpha-Beta Barrel ... Alpha-L-fucosidase, metazoa-type / Glycoside hydrolase, family 29 / Alpha-L-fucosidase / Alpha-L-fucosidase / Golgi alpha-mannosidase II / Glycosyl hydrolase, all-beta / Glycosidases / Glycoside hydrolase superfamily / TIM Barrel / Alpha-Beta Barrel / Immunoglobulin-like / Sandwich / Mainly Beta / Alpha Beta Similarity search - Domain/homologyBiological species Bacteroides thetaiotaomicron VPI-5482 (bacteria)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.7 Å DetailsAuthors Wu, L. / Davies, G.J. / Stubbs, K.A. / Coyle, T. / Debowski, A.W. Funding support Australia, United Kingdom, 3items Details Hide detailsOrganization Grant number Country Australian Research Council FT100100291 Australia National Health and Medical Research Council (Australia) APP1073250 Australia European Research Council ERC-2012-AdG-322942 United Kingdom
CitationJournal : Chembiochem / Year : 2019Title : Synthetic and Crystallographic Insight into Exploiting sp2Hybridization in the Development of alpha-l-Fucosidase Inhibitors.Authors : Coyle, T. / Wu, L. / Debowski, A.W. / Davies, G.J. / Stubbs, K.A. History Deposition Oct 24, 2018 Deposition site : PDBE / Processing site : PDBERevision 1.0 Feb 20, 2019 Provider : repository / Type : Initial releaseRevision 1.1 Jun 12, 2019 Group : Data collection / Database references / Category : citation / citation_author / pdbx_database_procItem : _citation.journal_volume / _citation.page_first ... _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.title / _citation_author.identifier_ORCID / _citation_author.name Revision 1.2 Jan 24, 2024 Group : Data collection / Database references / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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