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- PDB-6hnu: Crystal structure of the aminotransferase Aro8 from C. Albicans w... -
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Open data
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Basic information
Entry | Database: PDB / ID: 6hnu | ||||||
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Title | Crystal structure of the aminotransferase Aro8 from C. Albicans with ligands | ||||||
![]() | Aromatic amino acid aminotransferase I | ||||||
![]() | TRANSFERASE / Aro8 from C. Albicans | ||||||
Function / homology | ![]() transaminase activity / biosynthetic process / pyridoxal phosphate binding Similarity search - Function | ||||||
Biological species | ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Kiliszek, A. / Rzad, K. / Rypniewski, W. / Milewski, S. / Gabriel, I. | ||||||
Funding support | ![]()
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![]() | ![]() Title: Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties. Authors: Kiliszek, A. / Rypniewski, W. / Rzad, K. / Milewski, S. / Gabriel, I. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 230.4 KB | Display | ![]() |
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PDB format | ![]() | 181.9 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 489.6 KB | Display | ![]() |
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Full document | ![]() | 498.1 KB | Display | |
Data in XML | ![]() | 47.8 KB | Display | |
Data in CIF | ![]() | 73.1 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 6hnbSC ![]() 6hndC ![]() 6hnvC S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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Unit cell |
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Components
-Protein , 1 types, 2 molecules AB
#1: Protein | Mass: 54870.160 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() Production host: ![]() ![]() References: UniProt: C4YJ02 |
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-Non-polymers , 6 types, 1136 molecules ![](data/chem/img/BTB.gif)
![](data/chem/img/PLP.gif)
![](data/chem/img/PHE.gif)
![](data/chem/img/CL.gif)
![](data/chem/img/TRS.gif)
![](data/chem/img/HOH.gif)
![](data/chem/img/PLP.gif)
![](data/chem/img/PHE.gif)
![](data/chem/img/CL.gif)
![](data/chem/img/TRS.gif)
![](data/chem/img/HOH.gif)
#2: Chemical | #3: Chemical | #4: Chemical | #5: Chemical | ChemComp-CL / #6: Chemical | ChemComp-TRS / | #7: Water | ChemComp-HOH / | |
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-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.38 Å3/Da / Density % sol: 48.4 % |
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Crystal grow | Temperature: 293 K / Method: vapor diffusion, sitting drop / Details: 0.2 M MgCl2, 0.1 M Bis-Tris pH 5.5, 25% PEG 3350 |
-Data collection
Diffraction | Mean temperature: 100 K |
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Diffraction source | Source: ![]() ![]() ![]() |
Detector | Type: DECTRIS PILATUS 2M / Detector: PIXEL / Date: Jan 27, 2017 |
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 0.8943 Å / Relative weight: 1 |
Reflection | Resolution: 1.8→50 Å / Num. obs: 97014 / % possible obs: 99.6 % / Redundancy: 4.1 % / CC1/2: 0.997 / Rmerge(I) obs: 0.097 / Net I/σ(I): 11.29 |
Reflection shell | Resolution: 1.8→1.91 Å / Redundancy: 4.1 % / Mean I/σ(I) obs: 1.9 / Num. unique obs: 15338 / CC1/2: 0.687 / % possible all: 98.6 |
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Processing
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Refinement | Method to determine structure: ![]() Starting model: 6HNB Resolution: 1.8→45.33 Å / Cor.coef. Fo:Fc: 0.963 / Cor.coef. Fo:Fc free: 0.939 / Cross valid method: THROUGHOUT / ESU R: 0.126 / ESU R Free: 0.125 / Stereochemistry target values: MAXIMUM LIKELIHOOD / Details: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
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Solvent computation | Ion probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.2 Å / Solvent model: BABINET MODEL WITH MASK | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | Biso mean: 24.339 Å2
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Refinement step | Cycle: 1 / Resolution: 1.8→45.33 Å
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Refine LS restraints |
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