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Structure paper

TitleCrystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties.
Journal, issue, pagesJ. Struct. Biol., Vol. 205, Page 26-33, Year 2019
Publish dateSep 14, 2018 (structure data deposition date)
AuthorsKiliszek, A. / Rypniewski, W. / Rzad, K. / Milewski, S. / Gabriel, I.
External linksJ. Struct. Biol. / PubMed:30742897
MethodsX-ray diffraction
Resolution1.8 - 2.6 Å
Structure data

PDB-6hnb:
Crystal structure of aminotransferase Aro8 from Candida albicans
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

PDB-6hnd:
Crystal structure of the aromatic aminotransferase Aro9 from C. Albicans
Method: X-RAY DIFFRACTION / Resolution: 2.23 Å

PDB-6hnu:
Crystal structure of the aminotransferase Aro8 from C. Albicans with ligands
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-6hnv:
Crystal structure of aminotransferase Aro9 from C. Albicans with ligands
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-BTB:
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-SO4:
SULFATE ION

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-K:
Unknown entry

ChemComp-PHE:
PHENYLALANINE

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-BCN:
BICINE / pH buffer*YM

ChemComp-PPY:
3-PHENYLPYRUVIC ACID

ChemComp-UN1:
2-AMINOHEXANEDIOIC ACID

ChemComp-OOG:
2-OXOADIPIC ACID

Source
  • candida albicans wo-1 (yeast)
  • candida albicans (strain sc5314 / atcc mya-2876) (yeast)
  • candida albicans (yeast)
KeywordsTRANSFERASE / CaAro8 / Aro9 from C. Albicans / Aro8 from C. Albicans

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