Inhibition of replication initiation of damaged DNA by RB1/E2F1 / DNA replication initiation / Processive synthesis on the lagging strand / Removal of the Flap Intermediate / Polymerase switching / alpha DNA polymerase:primase complex / Activation of the pre-replicative complex / primosome complex / DNA replication, synthesis of primer / DNA replication initiation ...Inhibition of replication initiation of damaged DNA by RB1/E2F1 / DNA replication initiation / Processive synthesis on the lagging strand / Removal of the Flap Intermediate / Polymerase switching / alpha DNA polymerase:primase complex / Activation of the pre-replicative complex / primosome complex / DNA replication, synthesis of primer / DNA replication initiation / double-strand break repair / nuclear envelope / 4 iron, 4 sulfur cluster binding / DNA replication / DNA binding / nucleus / metal ion binding 類似検索 - 分子機能
DNA primase, large subunit, eukaryotic / DNA primase large subunit, eukaryotic/archaeal / Eukaryotic and archaeal DNA primase, large subunit 類似検索 - ドメイン・相同性
IRON/SULFUR CLUSTER / DNA primase large subunit 類似検索 - 構成要素
解像度: 1.82→29.28 Å / Cor.coef. Fo:Fc: 0.942 / Cor.coef. Fo:Fc free: 0.919 / WRfactor Rfree: 0.3544 / WRfactor Rwork: 0.3215 / FOM work R set: 0.4973 / SU B: 13.348 / SU ML: 0.32 / SU R Cruickshank DPI: 0.2038 / SU Rfree: 0.1889 / 交差検証法: THROUGHOUT / σ(F): 0 / ESU R: 0.204 / ESU R Free: 0.189 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : REFINED INDIVIDUALLY
Rfactor
反射数
%反射
Selection details
Rfree
0.3241
847
5.3 %
RANDOM
Rwork
0.2734
-
-
-
obs
0.276
15173
97 %
-
溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.2 Å / 溶媒モデル: MASK