- PDB-6djl: Crystal structure of the Rab11 GEF SH3BP5 bound to nucleotide fre... -
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Basic information
Entry
Database: PDB / ID: 6djl
Title
Crystal structure of the Rab11 GEF SH3BP5 bound to nucleotide free Rab11A
Components
Ras-related protein Rab-11A
SH3 domain-binding protein 5
Keywords
SIGNALING PROTEIN/PROTEIN TRANSPORT / Rab GTPase / Guanine nucleotide exchange factor / membrane trafficking / PROTEIN TRANSPORT / SIGNALING PROTEIN-PROTEIN TRANSPORT complex
Function / homology
Function and homology information
regulation of early endosome to recycling endosome transport / regulation of protein localization to centrosome / regulation of endocytic recycling / early endosome to recycling endosome transport / establishment of protein localization to organelle / establishment of vesicle localization / plasma membrane to endosome transport / postsynaptic recycling endosome / positive regulation of mitotic cytokinetic process / regulation of cilium assembly ...regulation of early endosome to recycling endosome transport / regulation of protein localization to centrosome / regulation of endocytic recycling / early endosome to recycling endosome transport / establishment of protein localization to organelle / establishment of vesicle localization / plasma membrane to endosome transport / postsynaptic recycling endosome / positive regulation of mitotic cytokinetic process / regulation of cilium assembly / exosomal secretion / amyloid-beta clearance by transcytosis / astral microtubule organization / melanosome transport / neurotransmitter receptor transport, endosome to postsynaptic membrane / VxPx cargo-targeting to cilium / protein transmembrane transport / regulation of vesicle-mediated transport / myosin V binding / RAB geranylgeranylation / Golgi to plasma membrane protein transport / multivesicular body assembly / protein localization to cilium / establishment of protein localization to membrane / syntaxin binding / protein localization to cell surface / TBC/RABGAPs / dynein light intermediate chain binding / mitotic metaphase chromosome alignment / protein kinase inhibitor activity / exocytosis / cleavage furrow / positive regulation of epithelial cell migration / mitotic spindle assembly / transport vesicle / vesicle-mediated transport / phagocytic vesicle / positive regulation of G2/M transition of mitotic cell cycle / multivesicular body / centriole / Anchoring of the basal body to the plasma membrane / cytoplasmic vesicle membrane / guanyl-nucleotide exchange factor activity / regulation of cytokinesis / small monomeric GTPase / trans-Golgi network membrane / protein localization to plasma membrane / Translocation of SLC2A4 (GLUT4) to the plasma membrane / trans-Golgi network / recycling endosome / SH3 domain binding / recycling endosome membrane / spindle pole / neuron projection development / Vasopressin regulates renal water homeostasis via Aquaporins / endocytic vesicle membrane / G protein activity / microtubule binding / cytoplasmic vesicle / vesicle / intracellular signal transduction / nuclear body / Golgi membrane / GTPase activity / centrosome / GTP binding / glutamatergic synapse / Golgi apparatus / signal transduction / protein-containing complex / mitochondrion / extracellular exosome / nucleoplasm / cytosol / cytoplasm Similarity search - Function
SH3-binding 5 / SH3 domain-binding protein 5 (SH3BP5) / : / Small GTPase Rab domain profile. / Ran (Ras-related nuclear proteins) /TC4 subfamily of small GTPases / Rho (Ras homology) subfamily of Ras-like small GTPases / Ras subfamily of RAS small GTPases / Small GTPase / Ras family / Rab subfamily of small GTPases ...SH3-binding 5 / SH3 domain-binding protein 5 (SH3BP5) / : / Small GTPase Rab domain profile. / Ran (Ras-related nuclear proteins) /TC4 subfamily of small GTPases / Rho (Ras homology) subfamily of Ras-like small GTPases / Ras subfamily of RAS small GTPases / Small GTPase / Ras family / Rab subfamily of small GTPases / Small GTP-binding protein domain / P-loop containing nucleotide triphosphate hydrolases / Rossmann fold / P-loop containing nucleoside triphosphate hydrolase / 3-Layer(aba) Sandwich / Alpha Beta Similarity search - Domain/homology
A: Ras-related protein Rab-11A B: SH3 domain-binding protein 5 C: SH3 domain-binding protein 5 D: SH3 domain-binding protein 5 E: SH3 domain-binding protein 5 F: Ras-related protein Rab-11A G: Ras-related protein Rab-11A H: Ras-related protein Rab-11A