登録情報 | データベース: PDB / ID: 6d27 |
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タイトル | Crystal structure of the prostaglandin D2 receptor CRTH2 with CAY10471 |
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要素 | Prostaglandin D2 receptor 2, Endolysin chimera |
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キーワード | MEMBRANE PROTEIN/ANTAGONIST / GPCR / MEMBRANE PROTEIN-ANTAGONIST complex |
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機能・相同性 | 機能・相同性情報
prostaglandin J receptor activity / prostaglandin D receptor activity / prostaglandin F receptor activity / complement receptor activity / Prostanoid ligand receptors / negative regulation of male germ cell proliferation / positive regulation of G protein-coupled receptor signaling pathway / neuropeptide binding / neuropeptide signaling pathway / viral release from host cell by cytolysis ...prostaglandin J receptor activity / prostaglandin D receptor activity / prostaglandin F receptor activity / complement receptor activity / Prostanoid ligand receptors / negative regulation of male germ cell proliferation / positive regulation of G protein-coupled receptor signaling pathway / neuropeptide binding / neuropeptide signaling pathway / viral release from host cell by cytolysis / adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway / peptidoglycan catabolic process / G protein-coupled receptor activity / calcium-mediated signaling / chemotaxis / cell wall macromolecule catabolic process / lysozyme / lysozyme activity / phospholipase C-activating G protein-coupled receptor signaling pathway / G alpha (i) signalling events / positive regulation of cytosolic calcium ion concentration / host cell cytoplasm / defense response to bacterium / inflammatory response / neuron projection / immune response / G protein-coupled receptor signaling pathway / plasma membrane類似検索 - 分子機能 Formyl peptide receptor-related / Endolysin T4 type / T4-type lysozyme / Glycoside hydrolase, family 24 / Lysozyme domain superfamily / Phage lysozyme / G-protein coupled receptors family 1 signature. / G protein-coupled receptor, rhodopsin-like / GPCR, rhodopsin-like, 7TM / G-protein coupled receptors family 1 profile. ...Formyl peptide receptor-related / Endolysin T4 type / T4-type lysozyme / Glycoside hydrolase, family 24 / Lysozyme domain superfamily / Phage lysozyme / G-protein coupled receptors family 1 signature. / G protein-coupled receptor, rhodopsin-like / GPCR, rhodopsin-like, 7TM / G-protein coupled receptors family 1 profile. / 7 transmembrane receptor (rhodopsin family) / Lysozyme-like domain superfamily類似検索 - ドメイン・相同性 Chem-FT4 / OLEIC ACID / DI(HYDROXYETHYL)ETHER / TRIETHYLENE GLYCOL / S-1,2-PROPANEDIOL / Endolysin / Prostaglandin D2 receptor 2類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト)
Enterobacteria phage T4 (ファージ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.738 Å |
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データ登録者 | Wang, L. / Yao, D. / Deepak, K. / Liu, H. / Gong, W. / Fan, H. / Wei, Z. / Zhang, C. |
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資金援助 | 中国, 1件 組織 | 認可番号 | 国 |
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National Natural Science Foundation of China (NSFC) | | 中国 |
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引用 | ジャーナル: Mol. Cell / 年: 2018 タイトル: Structures of the Human PGD2Receptor CRTH2 Reveal Novel Mechanisms for Ligand Recognition. 著者: Wang, L. / Yao, D. / Deepak, R.N.V.K. / Liu, H. / Xiao, Q. / Fan, H. / Gong, W. / Wei, Z. / Zhang, C. |
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履歴 | 登録 | 2018年4月13日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2018年10月3日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2019年4月17日 | Group: Data collection / Database references / カテゴリ: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
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改定 1.2 | 2020年1月8日 | Group: Author supporting evidence / カテゴリ: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization |
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改定 1.3 | 2023年10月4日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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