- PDB-6cej: Solution structure of a 14mer fragment of the p21 protein -
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基本情報
登録情報
データベース: PDB / ID: 6cej
タイトル
Solution structure of a 14mer fragment of the p21 protein
要素
Cyclin-dependent kinase inhibitor 1
キーワード
CELL CYCLE / PIP-box motif / p21 / PCNA
機能・相同性
機能・相同性情報
cyclin-dependent protein kinase activating kinase activity / cellular response to cell-matrix adhesion / negative regulation of cardiac muscle tissue regeneration / negative regulation of cyclin-dependent protein kinase activity / FOXO-mediated transcription of cell cycle genes / TFAP2 (AP-2) family regulates transcription of cell cycle factors / Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) / PCNA-p21 complex / intestinal epithelial cell maturation / p53-Dependent G1 DNA Damage Response ...cyclin-dependent protein kinase activating kinase activity / cellular response to cell-matrix adhesion / negative regulation of cardiac muscle tissue regeneration / negative regulation of cyclin-dependent protein kinase activity / FOXO-mediated transcription of cell cycle genes / TFAP2 (AP-2) family regulates transcription of cell cycle factors / Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) / PCNA-p21 complex / intestinal epithelial cell maturation / p53-Dependent G1 DNA Damage Response / regulation of cell cycle G1/S phase transition / tissue regeneration / Transcriptional regulation by RUNX2 / negative regulation of phosphorylation / negative regulation of DNA biosynthetic process / cyclin-dependent protein serine/threonine kinase inhibitor activity / response to arsenic-containing substance / negative regulation of vascular associated smooth muscle cell proliferation / Regulation of MITF-M-dependent genes involved in cell cycle and proliferation / positive regulation of programmed cell death / oncogene-induced cell senescence / Transcriptional activation of cell cycle inhibitor p21 / AKT phosphorylates targets in the cytosol / RUNX3 regulates CDKN1A transcription / Cyclin E associated events during G1/S transition / stress-induced premature senescence / DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator / negative regulation of G1/S transition of mitotic cell cycle / response to aldosterone / response to corticosterone / cellular response to UV-B / regulation of cyclin-dependent protein serine/threonine kinase activity / molecular function inhibitor activity / TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest / positive regulation of DNA replication / STAT5 activation downstream of FLT3 ITD mutants / protein kinase inhibitor activity / Cyclin A:Cdk2-associated events at S phase entry / cyclin-dependent protein kinase holoenzyme complex / regulation of G2/M transition of mitotic cell cycle / Constitutive Signaling by AKT1 E17K in Cancer / regulation of G1/S transition of mitotic cell cycle / mitotic G2 DNA damage checkpoint signaling / keratinocyte proliferation / cyclin binding / response to X-ray / replicative senescence / positive regulation of protein kinase activity / response to hyperoxia / intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator / animal organ regeneration / positive regulation of B cell proliferation / keratinocyte differentiation / : / protein sequestering activity / Signaling by FLT3 fusion proteins / DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest / cellular response to amino acid starvation / intrinsic apoptotic signaling pathway / negative regulation of protein phosphorylation / DNA Damage/Telomere Stress Induced Senescence / negative regulation of protein binding / molecular function activator activity / cellular response to ionizing radiation / Transcriptional regulation of granulopoiesis / SCF(Skp2)-mediated degradation of p27/p21 / wound healing / Cyclin D associated events in G1 / G1/S transition of mitotic cell cycle / cellular senescence / negative regulation of cell growth / response to toxic substance / cellular response to gamma radiation / positive regulation of fibroblast proliferation / protein import into nucleus / The role of GTSE1 in G2/M progression after G2 checkpoint / positive regulation of reactive oxygen species metabolic process / KEAP1-NFE2L2 pathway / Signaling by ALK fusions and activated point mutants / Senescence-Associated Secretory Phenotype (SASP) / Neddylation / heart development / cellular response to heat / fibroblast proliferation / Ras protein signal transduction / Interleukin-4 and Interleukin-13 signaling / in utero embryonic development / nuclear body / regulation of cell cycle / positive regulation of protein phosphorylation / response to xenobiotic stimulus / negative regulation of cell population proliferation / negative regulation of gene expression / DNA damage response / ubiquitin protein ligase binding / negative regulation of apoptotic process / protein-containing complex binding / nucleolus / protein kinase binding / perinuclear region of cytoplasm 類似検索 - 分子機能