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基本情報
登録情報 | データベース: PDB / ID: 6c4u | ||||||
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タイトル | Engineered FHA with Myc-pTBD peptide | ||||||
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![]() | PEPTIDE BINDING PROTEIN / FHA / Protein Engineering / Myc pT58 target | ||||||
機能・相同性 | ![]() SCF ubiquitin ligase complex binding / positive regulation of metanephric cap mesenchymal cell proliferation / deoxyribonucleoside triphosphate biosynthetic process / negative regulation of transcription initiation by RNA polymerase II / Myc-Max complex / RNA polymerase II transcription repressor complex / regulation of cell cycle process / regulation of somatic stem cell population maintenance / Binding of TCF/LEF:CTNNB1 to target gene promoters / meiotic recombination checkpoint signaling ...SCF ubiquitin ligase complex binding / positive regulation of metanephric cap mesenchymal cell proliferation / deoxyribonucleoside triphosphate biosynthetic process / negative regulation of transcription initiation by RNA polymerase II / Myc-Max complex / RNA polymerase II transcription repressor complex / regulation of cell cycle process / regulation of somatic stem cell population maintenance / Binding of TCF/LEF:CTNNB1 to target gene promoters / meiotic recombination checkpoint signaling / RUNX3 regulates WNT signaling / TFAP2 (AP-2) family regulates transcription of cell cycle factors / negative regulation of cell division / negative regulation of monocyte differentiation / negative regulation of phosphorylation / transcription regulator activator activity / Transcription of E2F targets under negative control by DREAM complex / response to growth factor / dual-specificity kinase / regulation of telomere maintenance / negative regulation of stress-activated MAPK cascade / fibroblast apoptotic process / Regulation of NFE2L2 gene expression / positive regulation of mesenchymal cell proliferation / protein-DNA complex disassembly / negative regulation of gene expression via chromosomal CpG island methylation / calcium/calmodulin-dependent protein kinase activity / branching involved in ureteric bud morphogenesis / Signaling by ALK / E-box binding / positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator / DNA replication origin binding / positive regulation of cysteine-type endopeptidase activity involved in apoptotic process / negative regulation of DNA damage checkpoint / DNA replication initiation / chromosome organization / regulation of DNA repair / Cyclin E associated events during G1/S transition / core promoter sequence-specific DNA binding / Cyclin A:Cdk2-associated events at S phase entry / negative regulation of fibroblast proliferation / : / ERK1 and ERK2 cascade / protein serine/threonine/tyrosine kinase activity / DNA damage checkpoint signaling / transcription coregulator binding / positive regulation of epithelial cell proliferation / response to gamma radiation / SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription / MAPK6/MAPK4 signaling / protein localization / NOTCH1 Intracellular Domain Regulates Transcription / Constitutive Signaling by NOTCH1 PEST Domain Mutants / Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants / DNA-binding transcription repressor activity, RNA polymerase II-specific / positive regulation of miRNA transcription / G1/S transition of mitotic cell cycle / Transcriptional regulation of granulopoiesis / cellular response to UV / MAPK cascade / positive regulation of fibroblast proliferation / cellular response to xenobiotic stimulus / cellular response to oxidative stress / cellular response to hypoxia / regulation of gene expression / DNA-binding transcription activator activity, RNA polymerase II-specific / protein tyrosine kinase activity / Interleukin-4 and Interleukin-13 signaling / DNA-binding transcription factor binding / intracellular iron ion homeostasis / Estrogen-dependent gene expression / protein dimerization activity / calmodulin binding / DNA-binding transcription factor activity, RNA polymerase II-specific / Ub-specific processing proteases / protein kinase activity / chromatin remodeling / response to xenobiotic stimulus / RNA polymerase II cis-regulatory region sequence-specific DNA binding / phosphorylation / DNA repair / protein serine kinase activity / protein serine/threonine kinase activity / DNA damage response / positive regulation of cell population proliferation / protein-containing complex binding / positive regulation of gene expression / chromatin / nucleolus / regulation of transcription by RNA polymerase II / negative regulation of apoptotic process / positive regulation of DNA-templated transcription / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / protein-containing complex / DNA binding / nucleoplasm / ATP binding / identical protein binding / nucleus 類似検索 - 分子機能 | ||||||
生物種 | ![]() ![]() ![]() | ||||||
手法 | ![]() ![]() ![]() | ||||||
![]() | Kall, S.L. / Lavie, A. | ||||||
![]() | ![]() タイトル: Generating a recombinant phosphothreonine-binding domain for a phosphopeptide of the human transcription factor, c-Myc. 著者: Venegas, L.A. / Kall, S.L. / Bankole, O. / Lavie, A. / Kay, B.K. | ||||||
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PDBx/mmCIF形式 | ![]() | 172.6 KB | 表示 | ![]() |
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文書・要旨 | ![]() | 534 KB | 表示 | ![]() |
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-関連構造データ
関連構造データ | ![]() 1g6gS S: 精密化の開始モデル |
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類似構造データ |
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リンク
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集合体
登録構造単位 | ![]()
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単位格子 |
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Components on special symmetry positions |
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非結晶学的対称性 (NCS) | NCSドメイン:
NCSドメイン領域: Component-ID: _ / Refine code: _
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