Entry | Database: PDB / ID: 6bpy |
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Title | Aspergillus fumigatus Thioredoxin Reductase |
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Components | Thioredoxin reductase |
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Keywords | OXIDOREDUCTASE / redox homeostasis / Rossmann fold / dithiol |
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Function / homology | Function and homology information
thioredoxin-disulfide reductase / thioredoxin-disulfide reductase (NADPH) activity / removal of superoxide radicals / cytoplasmSimilarity search - Function Thioredoxin reductase / Pyridine nucleotide-disulphide oxidoreductase, class-II, active site / Pyridine nucleotide-disulphide oxidoreductases class-II active site. / FAD/NAD(P)-binding domain / Pyridine nucleotide-disulphide oxidoreductase / FAD/NAD(P)-binding domain superfamilySimilarity search - Domain/homology ACETATE ION / FLAVIN-ADENINE DINUCLEOTIDE / FORMIC ACID / MALONATE ION / D-MALATE / NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE / Thioredoxin reductaseSimilarity search - Component |
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Biological species | ![](img/tx_fungus.gif) Neosartorya fumigata (mold) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 3.201 Å |
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Authors | Marshall, A.C. / Bruning, J.B. |
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Citation | Journal: Antimicrob.Agents Chemother. / Year: 2019 Title: Structure, Mechanism, and Inhibition ofAspergillus fumigatusThioredoxin Reductase. Authors: Marshall, A.C. / Kidd, S.E. / Lamont-Friedrich, S.J. / Arentz, G. / Hoffmann, P. / Coad, B.R. / Bruning, J.B. |
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History | Deposition | Nov 27, 2017 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Jan 9, 2019 | Provider: repository / Type: Initial release |
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Revision 1.1 | Sep 4, 2019 | Group: Data collection / Database references / Category: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
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Revision 1.2 | Oct 4, 2023 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ncs_dom_lim Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id |
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