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Open data
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Basic information
Entry | Database: PDB / ID: 5zny | ||||||
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Title | Structure of mDR3_DD-C363G with MBP tag | ||||||
![]() | Maltose-binding periplasmic protein,Tumor necrosis factor receptor superfamily, member 25 | ||||||
![]() | APOPTOSIS / TNFRSF25 / NF-kappa B / TRADD | ||||||
Function / homology | ![]() TNFs bind their physiological receptors / detection of maltose stimulus / maltose transport complex / carbohydrate transport / carbohydrate transmembrane transporter activity / maltose binding / maltose transport / maltodextrin transmembrane transport / ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing / ATP-binding cassette (ABC) transporter complex ...TNFs bind their physiological receptors / detection of maltose stimulus / maltose transport complex / carbohydrate transport / carbohydrate transmembrane transporter activity / maltose binding / maltose transport / maltodextrin transmembrane transport / ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing / ATP-binding cassette (ABC) transporter complex / cell chemotaxis / outer membrane-bounded periplasmic space / periplasmic space / apoptotic process / DNA damage response / signal transduction / membrane / plasma membrane Similarity search - Function | ||||||
Biological species | ![]() ![]() ![]() ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Yin, X. / Jin, T. | ||||||
![]() | ![]() Title: Crystal structure and activation mechanism of DR3 death domain. Authors: Yin, X. / Li, W. / Ma, H. / Zeng, W. / Peng, C. / Li, Y. / Liu, M. / Chen, Q. / Zhou, R. / Jin, T. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 698.5 KB | Display | ![]() |
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PDB format | ![]() | 581.3 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 493.8 KB | Display | ![]() |
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Full document | ![]() | 523.4 KB | Display | |
Data in XML | ![]() | 63.2 KB | Display | |
Data in CIF | ![]() | 84.9 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 5yevC ![]() 5ygpC ![]() 5ygsC ![]() 5znzC ![]() 1ompS S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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Unit cell |
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Components
#1: Protein | Mass: 51324.188 Da / Num. of mol.: 4 Mutation: D108A,K109A,E198A,N199A,K265A,E385A,K388A,D389A,I387V Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() Strain: K12 / Gene: malE, b4034, JW3994, Tnfrsf25, mCG_4090 / Production host: ![]() ![]() #2: Chemical | ChemComp-SO4 / #3: Water | ChemComp-HOH / | |
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-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.85 Å3/Da / Density % sol: 56.84 % |
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Crystal grow | Temperature: 291 K / Method: vapor diffusion, hanging drop / pH: 5.5 / Details: 2.2 M ammonium sulfate, 0.1 M MES pH 5.5 |
-Data collection
Diffraction | Mean temperature: 110 K |
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Diffraction source | Source: ![]() ![]() ![]() |
Detector | Type: DECTRIS PILATUS3 S 6M / Detector: PIXEL / Date: Nov 24, 2017 |
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 0.97776 Å / Relative weight: 1 |
Reflection | Resolution: 2.74→47.79 Å / Num. obs: 62248 / % possible obs: 99.8 % / Redundancy: 6.44 % / CC1/2: 0.999 / Net I/σ(I): 18.29 |
Reflection shell | Resolution: 2.74→2.91 Å / Num. unique obs: 62030 / CC1/2: 0.744 |
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Processing
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Refinement | Method to determine structure: ![]() Starting model: 1OMP Resolution: 2.74→47.78 Å / Cross valid method: FREE R-VALUE
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Refinement step | Cycle: LAST / Resolution: 2.74→47.78 Å
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LS refinement shell | Resolution: 2.74→2.838 Å | ||||||||||||||||||||||||||||||||||||||||
Refinement TLS params. | Method: refined / Origin x: 135.7524 Å / Origin y: 3.6678 Å / Origin z: 43.986 Å
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Refinement TLS group | Selection details: all |