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Structure paper

TitleCrystal structure and activation mechanism of DR3 death domain.
Journal, issue, pagesFebs J., Vol. 286, Page 2593-2610, Year 2019
Publish dateSep 19, 2017 (structure data deposition date)
AuthorsYin, X. / Li, W. / Ma, H. / Zeng, W. / Peng, C. / Li, Y. / Liu, M. / Chen, Q. / Zhou, R. / Jin, T.
External linksFebs J. / PubMed:30941855
MethodsX-ray diffraction
Resolution2.09 - 2.74 Å
Structure data

PDB-5yev:
Murine DR3 death domain
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-5ygp:
Human TNFRSF25 death domain mutant-D412E
Method: X-RAY DIFFRACTION / Resolution: 2.09 Å

PDB-5ygs:
Human TNFRSF25 death domain
Method: X-RAY DIFFRACTION / Resolution: 2.691 Å

PDB-5zny:
Structure of mDR3_DD-C363G with MBP tag
Method: X-RAY DIFFRACTION / Resolution: 2.74 Å

PDB-5znz:
Structure of mDR3 DD with MBP tag mutant-I387V
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
  • escherichia coli (strain k12) (bacteria)
KeywordsAPOPTOSIS / death domain / TNFRSF / NFkappaB / TNFRSF25 / TL1A / NF-kappa B / TRADD

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