Entry Database : PDB / ID : 5yo1 Structure visualization Downloads & linksTitle Structure of ePepN E298A mutant in complex with Puromycin ComponentsAminopeptidase N Details Keywords HYDROLASE / M1 class aminopeptidaseFunction / homology Function and homology informationFunction Domain/homology Component
membrane alanyl aminopeptidase / aminopeptidase activity / metallopeptidase activity / proteolysis / zinc ion binding / identical protein binding / plasma membrane Similarity search - Function Peptidase M1, alanyl aminopeptidase, C-terminal domain / Aminopeptidase N, middle-beta domain / Peptidase M1, alanyl aminopeptidase / Peptidase M1, alanyl aminopeptidase, C-terminal / Peptidase M1, alanyl aminopeptidase, Ig-like fold / Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily / Alanyl aminopeptidase, Ig-like domain superfamily / Domain of unknown function (DUF3458) Ig-like fold / Domain of unknown function (DUF3458_C) ARM repeats / Zincin-like fold ... Peptidase M1, alanyl aminopeptidase, C-terminal domain / Aminopeptidase N, middle-beta domain / Peptidase M1, alanyl aminopeptidase / Peptidase M1, alanyl aminopeptidase, C-terminal / Peptidase M1, alanyl aminopeptidase, Ig-like fold / Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily / Alanyl aminopeptidase, Ig-like domain superfamily / Domain of unknown function (DUF3458) Ig-like fold / Domain of unknown function (DUF3458_C) ARM repeats / Zincin-like fold / Zincin-like - #30 / Zincin-like / tricorn interacting facor f3 domain / Aminopeptidase N-like , N-terminal domain / Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase / Peptidase M1, membrane alanine aminopeptidase / Peptidase family M1 domain / Peptidase M1 N-terminal domain / Aminopeptidase N-like , N-terminal domain superfamliy / Neutral Protease Domain 2 / Neutral Protease; domain 2 / Peptidase M4/M1, CTD superfamily / Neutral zinc metallopeptidases, zinc-binding region signature. / Alpha Horseshoe / Immunoglobulin-like / Sandwich / 2-Layer Sandwich / Orthogonal Bundle / Mainly Beta / Mainly Alpha / Alpha Beta Similarity search - Domain/homologyBiological species Escherichia coli K12 (bacteria)Method X-RAY DIFFRACTION / MOLECULAR REPLACEMENT / Resolution : 2.5 Å DetailsAuthors Ganji, R.J. / Reddi, R. / Marapaka, A.K. / Addlagatta, A. Funding support India, 1items Details Hide detailsOrganization Grant number Country BT-BRB-TF-2-2011 India
CitationJournal : Int.J.Biol.Macromol. / Year : 2020Title : Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basisAuthors : Reddi, R. / Ganji, R.J. / Marapaka, A.K. / Bala, S.C. / Yerra, N.V. / Haque, N. / Addlagatta, A. History Deposition Oct 26, 2017 Deposition site : PDBJ / Processing site : PDBJRevision 1.0 Nov 7, 2018 Provider : repository / Type : Initial releaseRevision 1.1 Jul 27, 2022 Group : Database references / Category : citation / citation_author / database_2Item : _citation.country / _citation.journal_abbrev ... _citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.title / _citation.year / _database_2.pdbx_DOI / _database_2.pdbx_database_accession Revision 1.2 Nov 22, 2023 Group : Data collection / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model
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