- PDB-5vax: Bcl-2 complex with Beclin 1 BH3 domain -
+
Open data
ID or keywords:
Loading...
-
Basic information
Entry
Database: PDB / ID: 5vax
Title
Bcl-2 complex with Beclin 1 BH3 domain
Components
Apoptosis regulator Bcl-2 -- Bcl-2-like protein 1 Chimera
Beclin-1
Keywords
APOPTOSIS / Bcl-2 / autophagy / Beclin 1
Function / homology
Function and homology information
cellular response to aluminum ion / negative regulation of cellular pH reduction / negative regulation of retinal cell programmed cell death / pigment granule organization / CD8-positive, alpha-beta T cell lineage commitment / BAD-BCL-2 complex / positive regulation of skeletal muscle fiber development / regulation of glycoprotein biosynthetic process / positive regulation of stress granule assembly / phosphatidylinositol 3-kinase complex, class III ...cellular response to aluminum ion / negative regulation of cellular pH reduction / negative regulation of retinal cell programmed cell death / pigment granule organization / CD8-positive, alpha-beta T cell lineage commitment / BAD-BCL-2 complex / positive regulation of skeletal muscle fiber development / regulation of glycoprotein biosynthetic process / positive regulation of stress granule assembly / phosphatidylinositol 3-kinase complex, class III / positive regulation of melanocyte differentiation / cellular response to oxygen-glucose deprivation / channel inhibitor activity / melanin metabolic process / positive regulation of neuron maturation / phosphatidylinositol 3-kinase complex, class III, type II / phosphatidylinositol 3-kinase complex, class III, type I / myeloid cell apoptotic process / cochlear nucleus development / osteoblast proliferation / response to mitochondrial depolarisation / mesenchymal cell development / retinal cell programmed cell death / negative regulation of osteoblast proliferation / positive regulation of attachment of mitotic spindle microtubules to kinetochore / stem cell development / negative regulation of lysosome organization / gland morphogenesis / engulfment of apoptotic cell / renal system process / regulation of cell-matrix adhesion / The NLRP1 inflammasome / dendritic cell apoptotic process / ear development / positive regulation of autophagosome assembly / negative regulation of calcium ion transport into cytosol / early endosome to late endosome transport / negative regulation of autophagosome assembly / lymphoid progenitor cell differentiation / cytoplasmic side of mitochondrial outer membrane / melanocyte differentiation / T cell apoptotic process / receptor catabolic process / negative regulation of myeloid cell apoptotic process / negative regulation of epithelial cell apoptotic process / protein targeting to lysosome / SMAD protein signal transduction / BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members / late endosome to vacuole transport / regulation of nitrogen utilization / negative regulation of dendritic cell apoptotic process / glomerulus development / focal adhesion assembly / regulation of transmembrane transporter activity / negative regulation of T cell apoptotic process / oocyte development / metanephros development / B cell apoptotic process / neuron maturation / Regulation of MITF-M-dependent genes involved in apoptosis / negative regulation of motor neuron apoptotic process / positive regulation of multicellular organism growth / regulation of viral genome replication / endoplasmic reticulum calcium ion homeostasis / regulation of mitochondrial membrane permeability / phagophore assembly site / Translation of Replicase and Assembly of the Replication Transcription Complex / calcium ion transport into cytosol / response to UV-B / phosphatidylinositol-3-phosphate biosynthetic process / negative regulation of ossification / cellular response to nitrogen starvation / response to iron ion / negative regulation of programmed cell death / axon regeneration / epithelial cell apoptotic process / negative regulation of mitochondrial depolarization / motor neuron apoptotic process / positive regulation of smooth muscle cell migration / smooth muscle cell migration / NFE2L2 regulating tumorigenic genes / intrinsic apoptotic signaling pathway in response to oxidative stress / negative regulation of B cell apoptotic process / lysosome organization / organ growth / branching involved in ureteric bud morphogenesis / hair follicle morphogenesis / response to vitamin E / response to iron(II) ion / mitotic metaphase chromosome alignment / cytoplasmic pattern recognition receptor signaling pathway / negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator / positive regulation of cardiac muscle hypertrophy / digestive tract morphogenesis / B cell lineage commitment / negative regulation of G1/S transition of mitotic cell cycle / Macroautophagy / pore complex / RSV-host interactions / p38MAPK cascade Similarity search - Function
Beclin-1, BH3 domain / Beclin-1 BH3 domain, Bcl-2-interacting / Atg6/Beclin / Atg6/Beclin C-terminal domain superfamily / Atg6, BARA domain / Atg6/beclin, coiled-coil domain / Apg6 BARA domain / Apg6 coiled-coil region / Apoptosis regulator, Bcl-2 / Apoptosis regulator, Bcl-2/ BclX ...Beclin-1, BH3 domain / Beclin-1 BH3 domain, Bcl-2-interacting / Atg6/Beclin / Atg6/Beclin C-terminal domain superfamily / Atg6, BARA domain / Atg6/beclin, coiled-coil domain / Apg6 BARA domain / Apg6 coiled-coil region / Apoptosis regulator, Bcl-2 / Apoptosis regulator, Bcl-2/ BclX / Apoptosis regulator, Bcl-2, BH4 motif, conserved site / Apoptosis regulator, Bcl-2 family BH4 motif signature. / Apoptosis regulator, Bcl-2 protein, BH4 / Bcl-2 homology region 4 / Apoptosis regulator, Bcl-2 family BH4 motif profile. / BH4 Bcl-2 homology region 4 / Apoptosis regulator, Bcl-2, BH3 motif, conserved site / Apoptosis regulator, Bcl-2 family BH3 motif signature. / Apoptosis regulator, Bcl-2, BH1 motif, conserved site / Apoptosis regulator, Bcl-2 family BH1 motif signature. / Apoptosis regulator, Bcl-2, BH2 motif, conserved site / Apoptosis regulator, Bcl-2 family BH2 motif signature. / Bcl-2 family / BCL (B-Cell lymphoma); contains BH1, BH2 regions / Bcl2-like / Bcl-2, Bcl-2 homology region 1-3 / Apoptosis regulator proteins, Bcl-2 family / BCL2-like apoptosis inhibitors family profile. / Bcl-2-like superfamily Similarity search - Domain/homology
In the structure databanks used in Yorodumi, some data are registered as the other names, "COVID-19 virus" and "2019-nCoV". Here are the details of the virus and the list of structure data.
Jan 31, 2019. EMDB accession codes are about to change! (news from PDBe EMDB page)
EMDB accession codes are about to change! (news from PDBe EMDB page)
The allocation of 4 digits for EMDB accession codes will soon come to an end. Whilst these codes will remain in use, new EMDB accession codes will include an additional digit and will expand incrementally as the available range of codes is exhausted. The current 4-digit format prefixed with “EMD-” (i.e. EMD-XXXX) will advance to a 5-digit format (i.e. EMD-XXXXX), and so on. It is currently estimated that the 4-digit codes will be depleted around Spring 2019, at which point the 5-digit format will come into force.
The EM Navigator/Yorodumi systems omit the EMD- prefix.
Related info.:Q: What is EMD? / ID/Accession-code notation in Yorodumi/EM Navigator
Yorodumi is a browser for structure data from EMDB, PDB, SASBDB, etc.
This page is also the successor to EM Navigator detail page, and also detail information page/front-end page for Omokage search.
The word "yorodu" (or yorozu) is an old Japanese word meaning "ten thousand". "mi" (miru) is to see.
Related info.:EMDB / PDB / SASBDB / Comparison of 3 databanks / Yorodumi Search / Aug 31, 2016. New EM Navigator & Yorodumi / Yorodumi Papers / Jmol/JSmol / Function and homology information / Changes in new EM Navigator and Yorodumi