登録情報 データベース : PDB / ID : 5tfx 構造の表示 ダウンロードとリンクタイトル New method for synthesis of benzoxazole amide inhibitors of carbonic anhydrase 要素Carbonic anhydrase 2 詳細 キーワード Lyase/Lyase Inhibitor / carbonic anhydrase mimic / inhibitor / Lyase-Lyase Inhibitor complex機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
positive regulation of cellular pH reduction / positive regulation of dipeptide transmembrane transport / regulation of monoatomic anion transport / secretion / cyanamide hydratase / cyanamide hydratase activity / arylesterase activity / regulation of chloride transport / Reversible hydration of carbon dioxide / morphogenesis of an epithelium ... positive regulation of cellular pH reduction / positive regulation of dipeptide transmembrane transport / regulation of monoatomic anion transport / secretion / cyanamide hydratase / cyanamide hydratase activity / arylesterase activity / regulation of chloride transport / Reversible hydration of carbon dioxide / morphogenesis of an epithelium / angiotensin-activated signaling pathway / regulation of intracellular pH / positive regulation of synaptic transmission, GABAergic / carbonic anhydrase / carbonate dehydratase activity / carbon dioxide transport / Erythrocytes take up oxygen and release carbon dioxide / Erythrocytes take up carbon dioxide and release oxygen / neuron cellular homeostasis / apical part of cell / myelin sheath / extracellular exosome / zinc ion binding / plasma membrane / cytosol / cytoplasm 類似検索 - 分子機能 Carbonic Anhydrase II / Alpha carbonic anhydrase / Carbonic anhydrase, alpha-class, conserved site / Alpha-carbonic anhydrases signature. / Carbonic anhydrase, alpha-class / Alpha carbonic anhydrase domain / Alpha carbonic anhydrase domain superfamily / Eukaryotic-type carbonic anhydrase / Alpha-carbonic anhydrases profile. / Eukaryotic-type carbonic anhydrase ... Carbonic Anhydrase II / Alpha carbonic anhydrase / Carbonic anhydrase, alpha-class, conserved site / Alpha-carbonic anhydrases signature. / Carbonic anhydrase, alpha-class / Alpha carbonic anhydrase domain / Alpha carbonic anhydrase domain superfamily / Eukaryotic-type carbonic anhydrase / Alpha-carbonic anhydrases profile. / Eukaryotic-type carbonic anhydrase / Roll / Alpha Beta 類似検索 - ドメイン・相同性 N-(5-sulfamoyl-1,3-benzoxazol-2-yl)benzamide / Carbonic anhydrase 2 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.5 Å 詳細データ登録者 Peat, T.S. / Supuran, C. 引用ジャーナル : Org. Biomol. Chem. / 年 : 2016タイトル : Intramolecular oxidative deselenization of acylselenoureas: a facile synthesis of benzoxazole amides and carbonic anhydrase inhibitors.著者 : Angeli, A. / Peat, T.S. / Bartolucci, G. / Nocentini, A. / Supuran, C.T. / Carta, F. 履歴 登録 2016年9月26日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2017年8月9日 Provider : repository / タイプ : Initial release改定 1.1 2017年9月27日 Group : Author supporting evidence / カテゴリ : pdbx_audit_support改定 1.2 2023年10月4日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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