Entry | Database: PDB / ID: 5tbx |
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Title | hnRNP A18 RNA Recognition Motif |
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Components | Cold-inducible RNA-binding protein |
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Keywords | RNA BINDING PROTEIN / RNA-binding protein |
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Function / homology | Function and homology information
mRNA stabilization / positive regulation of mRNA splicing, via spliceosome / stress granule assembly / response to UV / translation repressor activity / response to cold / mRNA 3'-UTR binding / positive regulation of translation / spliceosomal complex / cytoplasmic stress granule ...mRNA stabilization / positive regulation of mRNA splicing, via spliceosome / stress granule assembly / response to UV / translation repressor activity / response to cold / mRNA 3'-UTR binding / positive regulation of translation / spliceosomal complex / cytoplasmic stress granule / small ribosomal subunit rRNA binding / RNA binding / nucleoplasm / nucleus / cytoplasmSimilarity search - Function RBM3/CIRBP, RNA recognition motif / RNA recognition motif domain, eukaryote / RNA recognition motif / RRM (RNA recognition motif) domain / RNA recognition motif / RNA recognition motif / Eukaryotic RNA Recognition Motif (RRM) profile. / RNA recognition motif domain / RNA-binding domain superfamily / Nucleotide-binding alpha-beta plait domain superfamily ...RBM3/CIRBP, RNA recognition motif / RNA recognition motif domain, eukaryote / RNA recognition motif / RRM (RNA recognition motif) domain / RNA recognition motif / RNA recognition motif / Eukaryotic RNA Recognition Motif (RRM) profile. / RNA recognition motif domain / RNA-binding domain superfamily / Nucleotide-binding alpha-beta plait domain superfamily / Alpha-Beta Plaits / 2-Layer Sandwich / Alpha BetaSimilarity search - Domain/homology |
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Biological species | Homo sapiens (human) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 1.767 Å |
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Authors | Coburn, K.M. / Melville, Z. / Aligholizadeh, E. / Roth, B.M. / Varney, K.M. / Weber, D.J. |
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Funding support | United States, 2items Organization | Grant number | Country |
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National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | GM-58888 | United States | National Institutes of Health/National Cancer Institute (NIH/NCI) | CA-107331 | United States |
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Citation | Journal: Acta Crystallogr F Struct Biol Commun / Year: 2017 Title: Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif. Authors: Coburn, K. / Melville, Z. / Aligholizadeh, E. / Roth, B.M. / Varney, K.M. / Carrier, F. / Pozharski, E. / Weber, D.J. |
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History | Deposition | Sep 13, 2016 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Apr 12, 2017 | Provider: repository / Type: Initial release |
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Revision 1.1 | Apr 19, 2017 | Group: Database references |
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Revision 1.2 | Sep 27, 2017 | Group: Author supporting evidence / Category: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization |
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Revision 1.3 | Dec 4, 2019 | Group: Author supporting evidence / Category: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization |
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Revision 1.4 | Mar 6, 2024 | Group: Data collection / Database references / Derived calculations Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_struct_conn_angle / struct_conn Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr2_auth_seq_id |
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Revision 1.5 | Apr 3, 2024 | Group: Refinement description / Category: pdbx_initial_refinement_model |
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