Entry | Database: PDB / ID: 5ol6 |
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Title | Crystal structure of an inactivated Npu SICLOPPS intein with CAFHPQ extein |
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Components | Nucleic acid binding, OB-fold, tRNA/helicase-type,DNA-directed DNA polymerase |
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Keywords | SPLICING / intein / extein / SICLOPPS / cyclic peptide |
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Function / homology | Function and homology information
intein-mediated protein splicing / 3'-5' exonuclease activity / helicase activity / DNA replication / nucleic acid binding / DNA-directed DNA polymerase / DNA-directed DNA polymerase activitySimilarity search - Function Bacterial DNA polymerase III alpha subunit, thumb domain / DNA polymerase III, alpha subunit / Bacterial DNA polymerase III, alpha subunit, NTPase domain / DNA polymerase, helix-hairpin-helix motif / DNA polymerase III alpha subunit finger domain / Bacterial DNA polymerase III alpha NTPase domain / Helix-hairpin-helix motif / Bacterial DNA polymerase III alpha subunit finger domain / PHP domain / PHP domain ...Bacterial DNA polymerase III alpha subunit, thumb domain / DNA polymerase III, alpha subunit / Bacterial DNA polymerase III, alpha subunit, NTPase domain / DNA polymerase, helix-hairpin-helix motif / DNA polymerase III alpha subunit finger domain / Bacterial DNA polymerase III alpha NTPase domain / Helix-hairpin-helix motif / Bacterial DNA polymerase III alpha subunit finger domain / PHP domain / PHP domain / Polymerase/histidinol phosphatase, N-terminal / DNA polymerase alpha chain like domain / Polymerase/histidinol phosphatase-like / Intein C-terminal splicing region / Intein C-terminal splicing motif profile. / Intein N-terminal splicing region / Intein N-terminal splicing motif profile. / Hint domain N-terminal / Hint (Hedgehog/Intein) domain N-terminal region / OB-fold nucleic acid binding domain, AA-tRNA synthetase-type / Hint domain superfamily / OB-fold nucleic acid binding domainSimilarity search - Domain/homology |
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Biological species | Nostoc punctiforme (bacteria) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2 Å |
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Authors | Kick, L.M. / Schneider, S. |
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Funding support | Germany, 4items Organization | Grant number | Country |
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Center for Integrated Protein Science | | Germany | German Research Foundation | SCHN1273 | Germany | German Research Foundation | SFB749 | Germany | Fonds der chemischen Industrie | | Germany |
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Citation | Journal: Chembiochem / Year: 2017 Title: Mechanistic Insights into Cyclic Peptide Generation by DnaE Split-Inteins through Quantitative and Structural Investigation. Authors: Kick, L.M. / Harteis, S. / Koch, M.F. / Schneider, S. |
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History | Deposition | Jul 26, 2017 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | Sep 27, 2017 | Provider: repository / Type: Initial release |
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Revision 1.1 | Nov 29, 2017 | Group: Database references / Category: citation / citation_author Item: _citation.journal_volume / _citation.page_first ..._citation.journal_volume / _citation.page_first / _citation.page_last / _citation.title / _citation_author.name |
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