[English] 日本語
Yorodumi- PDB-5nbl: Crystal structure of the Arp4-N-actin(APO-state) heterodimer boun... -
+Open data
-Basic information
Entry | Database: PDB / ID: 5nbl | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Title | Crystal structure of the Arp4-N-actin(APO-state) heterodimer bound by a nanobody | ||||||||||||
Components |
| ||||||||||||
Keywords | HYDROLASE / Nuclear actin / Actin-related-proteins / Chromatin remodeling / Nanobody / INO80 / SWR1 / NuA4 | ||||||||||||
Function / homology | Function and homology information mitotic actomyosin contractile ring contraction / RHOA GTPase cycle / cellular bud neck contractile ring / RHO GTPases activate IQGAPs / RHO GTPases Activate WASPs and WAVEs / Regulation of actin dynamics for phagocytic cup formation / ascospore wall assembly / vacuole inheritance / actin cortical patch / Swr1 complex ...mitotic actomyosin contractile ring contraction / RHOA GTPase cycle / cellular bud neck contractile ring / RHO GTPases activate IQGAPs / RHO GTPases Activate WASPs and WAVEs / Regulation of actin dynamics for phagocytic cup formation / ascospore wall assembly / vacuole inheritance / actin cortical patch / Swr1 complex / Platelet degranulation / : / Ino80 complex / kinetochore assembly / SWI/SNF complex / NuA4 histone acetyltransferase complex / establishment of cell polarity / actin filament bundle / protein secretion / actin filament / Hydrolases; Acting on acid anhydrides; Acting on acid anhydrides to facilitate cellular and subcellular movement / structural constituent of cytoskeleton / endocytosis / chromatin organization / histone binding / hydrolase activity / chromatin remodeling / DNA repair / DNA-templated transcription / chromatin binding / chromatin / regulation of DNA-templated transcription / regulation of transcription by RNA polymerase II / ATP binding / identical protein binding / nucleus Similarity search - Function | ||||||||||||
Biological species | Saccharomyces cerevisiae (brewer's yeast) Vicugna pacos (alpaca) Trichoplusia ni (cabbage looper) | ||||||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 2.8 Å | ||||||||||||
Authors | Knoll, K.R. / Eustermann, S. / Hopfner, K.P. | ||||||||||||
Funding support | 3items
| ||||||||||||
Citation | Journal: Nat. Struct. Mol. Biol. / Year: 2018 Title: The nuclear actin-containing Arp8 module is a linker DNA sensor driving INO80 chromatin remodeling. Authors: Knoll, K.R. / Eustermann, S. / Niebauer, V. / Oberbeckmann, E. / Stoehr, G. / Schall, K. / Tosi, A. / Schwarz, M. / Buchfellner, A. / Korber, P. / Hopfner, K.P. | ||||||||||||
History |
|
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
---|
-Downloads & links
-Download
PDBx/mmCIF format | 5nbl.cif.gz | 369.6 KB | Display | PDBx/mmCIF format |
---|---|---|---|---|
PDB format | pdb5nbl.ent.gz | 294.6 KB | Display | PDB format |
PDBx/mmJSON format | 5nbl.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/nb/5nbl ftp://data.pdbj.org/pub/pdb/validation_reports/nb/5nbl | HTTPS FTP |
---|
-Related structure data
Related structure data | 5nbmC 5nbnC 1yagS 3qb0S C: citing same article (ref.) S: Starting model for refinement |
---|---|
Similar structure data |
-Links
-Assembly
Deposited unit |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
2 |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Unit cell |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
|