+
Open data
-
Basic information
Entry | Database: PDB / ID: 5mjx | ||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Title | 2'F-ANA/DNA Chimeric TBA Quadruplex structure | ||||||||||||||||||||
![]() | DNA (5'-D(*![]() DNA / 2'F-ANA/DNA TBA Structure / Structure from MOLMOL | Function / homology | DNA / DNA (> 10) | ![]() Biological species | synthetic construct (others) | Method | SOLUTION NMR / molecular dynamics | ![]() Lietard, J. / Abou Assi, H. / Gomez-Pinto, I. / Gonzalez, C. / Somoza, M.M. / Damha, M.J. | ![]() ![]() Title: Mapping the affinity landscape of Thrombin-binding aptamers on 2 F-ANA/DNA chimeric G-Quadruplex microarrays. Authors: Lietard, J. / Abou Assi, H. / Gomez-Pinto, I. / Gonzalez, C. / Somoza, M.M. / Damha, M.J. History |
|
-
Structure visualization
Structure viewer | Molecule: ![]() ![]() |
---|
-
Downloads & links
-
Download
PDBx/mmCIF format | ![]() | 99.6 KB | Display | ![]() |
---|---|---|---|---|
PDB format | ![]() | 80.8 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 400 KB | Display | ![]() |
---|---|---|---|---|
Full document | ![]() | 581.3 KB | Display | |
Data in XML | ![]() | 29.7 KB | Display | |
Data in CIF | ![]() | 23.9 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Similar structure data | |
---|---|
Other databases |
|
-
Links
-
Assembly
Deposited unit | ![]()
| |||||||||
---|---|---|---|---|---|---|---|---|---|---|
1 |
| |||||||||
NMR ensembles |
|
-
Components
#1: DNA chain | Mass: 4761.042 Da / Num. of mol.: 1 / Source method: obtained synthetically / Source: (synth.) synthetic construct (others) |
---|
-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NMR experiment |
|
-
Sample preparation
Details | Type: solution Contents: 1.0 mg/mL DNA (5'-D(*GP*GP*(FT)P*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3'), 90% H2O/10% D2O Label: 1H_sample / Solvent system: 90% H2O/10% D2O |
---|---|
Sample | Conc.: 1.0 mg/mL Component: DNA (5'-D(*GP*GP*(FT)P*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3') Isotopic labeling: natural abundance |
Sample conditions | Details: 10mM NaPi, 25mM KCl / Ionic strength: 10mM NaPi, 25mM KCl mM / Label: condicions_1 / pH: 7.0 / Pressure: 1 atm / Temperature: 279.6 K |
-NMR measurement
NMR spectrometer |
|
---|
-
Processing
NMR software |
| |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Refinement | Method: molecular dynamics / Software ordinal: 1 | |||||||||||||||
NMR representative | Selection criteria: minimized average structure | |||||||||||||||
NMR ensemble | Conformer selection criteria: structures with the lowest energy Conformers calculated total number: 15 / Conformers submitted total number: 10 |