Entry | Database: PDB / ID: 5lpf |
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Title | Kallikrein-related peptidase 10 |
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Components | Kallikrein-10 |
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Keywords | HYDROLASE / Serine protease / zymogen-like enzyme / Zn2+ inhibition / tumor suppressor |
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Function / homology | Function and homology information
Hydrolases; Acting on peptide bonds (peptidases); Serine endopeptidases / serine-type peptidase activity / cell cycle / serine-type endopeptidase activity / proteolysis / extracellular regionSimilarity search - Function Serine proteases, trypsin family, histidine active site / Peptidase S1A, chymotrypsin family / Serine proteases, trypsin family, histidine active site. / Serine proteases, trypsin domain profile. / Trypsin-like serine protease / Serine proteases, trypsin domain / Trypsin / Trypsin-like serine proteases / Thrombin, subunit H / Peptidase S1, PA clan, chymotrypsin-like fold ...Serine proteases, trypsin family, histidine active site / Peptidase S1A, chymotrypsin family / Serine proteases, trypsin family, histidine active site. / Serine proteases, trypsin domain profile. / Trypsin-like serine protease / Serine proteases, trypsin domain / Trypsin / Trypsin-like serine proteases / Thrombin, subunit H / Peptidase S1, PA clan, chymotrypsin-like fold / Peptidase S1, PA clan / Beta Barrel / Mainly BetaSimilarity search - Domain/homology |
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Biological species | Homo sapiens (human) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 2.7 Å |
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Authors | Goettig, P. / Debela, M. / Magdolen, V. / Bode, W. / Brandstetter, H. |
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Funding support | Austria, 1items Organization | Grant number | Country |
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Austrian Science Fund | P25003-B21 | Austria |
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Citation | Journal: Biol.Chem. / Year: 2016 Title: Structural basis for the Zn2+ inhibition of the zymogen-like kallikrein-related peptidase 10. Authors: Debela, M. / Magdolen, V. / Bode, W. / Brandstetter, H. / Goettig, P. |
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History | Deposition | Aug 12, 2016 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | Oct 5, 2016 | Provider: repository / Type: Initial release |
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Revision 1.1 | Nov 16, 2016 | Group: Database references |
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Revision 1.2 | Sep 6, 2017 | Group: Advisory / Author supporting evidence / Category: pdbx_audit_support / pdbx_unobs_or_zero_occ_atoms / Item: _pdbx_audit_support.funding_organization |
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Revision 1.3 | Jan 10, 2024 | Group: Advisory / Data collection ...Advisory / Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_unobs_or_zero_occ_atoms / struct_ncs_dom_lim Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id |
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