Entry Database : PDB / ID : 5j67 Structure visualization Downloads & linksTitle Structure of Astrotactin-2, a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development ComponentsAstrotactin-2 Details Keywords MEMBRANE PROTEIN / MACPF / annexin-like / fibronectin / neural guidanceFunction / homology Function and homology informationFunction Domain/homology Component
establishment of body hair planar orientation / inositol 1,3,4,5 tetrakisphosphate binding / cell pole / negative regulation of protein localization to cell surface / neuron cell-cell adhesion / protein localization to cell surface / clathrin-coated vesicle / neuron migration / late endosome / protein transport ... establishment of body hair planar orientation / inositol 1,3,4,5 tetrakisphosphate binding / cell pole / negative regulation of protein localization to cell surface / neuron cell-cell adhesion / protein localization to cell surface / clathrin-coated vesicle / neuron migration / late endosome / protein transport / cell cortex / perikaryon / early endosome / endosome / calcium ion binding / membrane Similarity search - Function Astrotactin / Astrotactin-2, C-terminal beta-hairpin domain / Annexin-like domain / Astrotactin-1/2, EGF-like and Fn(III) domains / Astrotactin-1/2, N-terminal / Annexin-like domain / Astrotactin-2 C-terminal beta-hairpin domain / Astrotactin 1/2 N-terminal / ASTN1/2 Fn3 domain / membrane-attack complex / perforin ... Astrotactin / Astrotactin-2, C-terminal beta-hairpin domain / Annexin-like domain / Astrotactin-1/2, EGF-like and Fn(III) domains / Astrotactin-1/2, N-terminal / Annexin-like domain / Astrotactin-2 C-terminal beta-hairpin domain / Astrotactin 1/2 N-terminal / ASTN1/2 Fn3 domain / membrane-attack complex / perforin / MAC/Perforin domain / Membrane attack complex component/perforin (MACPF) domain / Fibronectin type III superfamily Similarity search - Domain/homologyBiological species Homo sapiens (human)Method X-RAY DIFFRACTION / SYNCHROTRON / SIRAS / Resolution : 3.16 Å DetailsAuthors Ni, T. / Harlos, K. / Gilbert, R.J.C. Funding support United Kingdom, 1items Details Hide detailsOrganization Grant number Country Medical Research Council (United Kingdom) MR/N000331/1 United Kingdom
CitationJournal : Open Biology / Year : 2016Title : Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.Authors : Ni, T. / Harlos, K. / Gilbert, R. History Deposition Apr 4, 2016 Deposition site : RCSB / Processing site : PDBERevision 1.0 May 25, 2016 Provider : repository / Type : Initial releaseRevision 1.1 Jun 15, 2016 Group : Database referencesRevision 1.2 Sep 13, 2017 Group : Author supporting evidence / Category : pdbx_audit_support / Item : _pdbx_audit_support.funding_organizationRevision 1.3 Apr 3, 2019 Group : Data collection / Source and taxonomy / Category : entity_src_gen / Item : _entity_src_gen.pdbx_host_org_cell_lineRevision 2.0 Jul 29, 2020 Group : Advisory / Atomic model ... Advisory / Atomic model / Data collection / Derived calculations / Source and taxonomy / Structure summary Category : atom_site / chem_comp ... atom_site / chem_comp / database_PDB_caveat / entity / entity_src_gen / pdbx_branch_scheme / pdbx_chem_comp_identifier / pdbx_entity_branch / pdbx_entity_branch_descriptor / pdbx_entity_branch_link / pdbx_entity_branch_list / pdbx_entity_nonpoly / pdbx_nonpoly_scheme / pdbx_struct_assembly_gen / pdbx_validate_chiral / struct_asym / struct_conn / struct_site / struct_site_gen Item : _atom_site.B_iso_or_equiv / _atom_site.Cartn_x ... _atom_site.B_iso_or_equiv / _atom_site.Cartn_x / _atom_site.Cartn_y / _atom_site.Cartn_z / _atom_site.auth_asym_id / _atom_site.auth_atom_id / _atom_site.auth_comp_id / _atom_site.auth_seq_id / _atom_site.label_asym_id / _atom_site.label_atom_id / _atom_site.label_comp_id / _atom_site.label_entity_id / _atom_site.type_symbol / _chem_comp.name / _chem_comp.type / _database_PDB_caveat.text / _entity_src_gen.entity_id / _pdbx_struct_assembly_gen.asym_id_list / _pdbx_validate_chiral.auth_asym_id / _pdbx_validate_chiral.auth_seq_id / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_role / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id Description : Carbohydrate remediation / Provider : repository / Type : RemediationRevision 2.1 Nov 13, 2024 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description / Structure summary Category : chem_comp / chem_comp_atom ... chem_comp / chem_comp_atom / chem_comp_bond / database_2 / pdbx_entry_details / pdbx_modification_feature / struct_conn / struct_ncs_dom_lim Item : _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI ... _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_leaving_atom_flag / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id
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