登録情報 データベース : PDB / ID : 5izu 構造の表示 ダウンロードとリンクタイトル A new binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function 要素SH3 and multiple ankyrin repeat domains protein 3 peptide from Disks large-associated protein 3 詳細キーワード PROTEIN BINDING / Shank / SAPAP / PDZ / extension / synapse / specific interaction機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
response to interleukin-17 / regulation of AMPA glutamate receptor clustering / Neurexins and neuroligins / guanylate kinase-associated protein clustering / striatal medium spiny neuron differentiation / positive regulation of synapse structural plasticity / synaptic receptor adaptor activity / postsynaptic density assembly / embryonic epithelial tube formation / regulation of grooming behavior ... response to interleukin-17 / regulation of AMPA glutamate receptor clustering / Neurexins and neuroligins / guanylate kinase-associated protein clustering / striatal medium spiny neuron differentiation / positive regulation of synapse structural plasticity / synaptic receptor adaptor activity / postsynaptic density assembly / embryonic epithelial tube formation / regulation of grooming behavior / postsynaptic specialization / structural constituent of postsynaptic density / negative regulation of actin filament bundle assembly / cholinergic synapse / positive regulation of long-term neuronal synaptic plasticity / modification of postsynaptic structure / signaling / NMDA glutamate receptor clustering / negative regulation of cell volume / RET signaling / vocalization behavior / neuron spine / AMPA glutamate receptor clustering / positive regulation of glutamate receptor signaling pathway / regulation of dendritic spine morphogenesis / regulation of behavioral fear response / dendritic spine morphogenesis / locomotion / brain morphogenesis / regulation of long-term synaptic potentiation / long-term synaptic depression / neural precursor cell proliferation / ciliary membrane / regulation of long-term synaptic depression / positive regulation of dendritic spine development / exploration behavior / locomotory exploration behavior / associative learning / neuromuscular process controlling balance / excitatory synapse / social behavior / positive regulation of excitatory postsynaptic potential / glial cell proliferation / synapse assembly / ionotropic glutamate receptor binding / positive regulation of synaptic transmission, glutamatergic / positive regulation of long-term synaptic potentiation / learning / locomotory behavior / modulation of chemical synaptic transmission / neuromuscular junction / regulation of synaptic plasticity / SH3 domain binding / long-term synaptic potentiation / memory / MAPK cascade / amyloid-beta binding / actin binding / scaffold protein binding / dendritic spine / gene expression / learning or memory / neuron projection / postsynaptic density / synapse / glutamatergic synapse / zinc ion binding / plasma membrane / cytoplasm 類似検索 - 分子機能 SAPAP family / Guanylate-kinase-associated protein (GKAP) protein / : / PDZ domain 6 / PDZ domain / Variant SH3 domain / SAM domain (Sterile alpha motif) / PDZ domain / Pdz3 Domain / SAM domain profile. ... SAPAP family / Guanylate-kinase-associated protein (GKAP) protein / : / PDZ domain 6 / PDZ domain / Variant SH3 domain / SAM domain (Sterile alpha motif) / PDZ domain / Pdz3 Domain / SAM domain profile. / Sterile alpha motif. / Sterile alpha motif domain / Sterile alpha motif/pointed domain superfamily / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. / PDZ domain / PDZ superfamily / Ankyrin repeats (3 copies) / Ankyrin repeat profile. / Ankyrin repeat region circular profile. / ankyrin repeats / Ankyrin repeat / Ankyrin repeat-containing domain superfamily / Src homology 3 domains / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3 domain / Roll / Mainly Beta 類似検索 - ドメイン・相同性 SH3 and multiple ankyrin repeat domains protein 3 / Disks large-associated protein 3 類似検索 - 構成要素生物種 Mus musculus (ハツカネズミ)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.494 Å 詳細データ登録者 Shang, Y. / Zeng, M. / Zhang, M. 資金援助 香港, 中国, 5件 詳細 詳細を隠す組織 認可番号 国 Research Grants Council 663811 香港 Research Grants Council 663812 香港 Research Grants Council T13-607/12R 香港 Research Grants Council AoE-M09-12 香港 Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology) 2014CB910204 中国
引用ジャーナル : Proc.Natl.Acad.Sci.USA / 年 : 2016タイトル : A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function著者 : Zeng, M. / Shang, Y. / Guo, T. / He, Q. / Yung, W.H. / Liu, K. / Zhang, M. 履歴 登録 2016年3月26日 登録サイト : RCSB / 処理サイト : PDBJ改定 1.0 2016年5月18日 Provider : repository / タイプ : Initial release改定 1.1 2016年6月1日 Group : Database references改定 1.2 2016年6月15日 Group : Database references改定 1.3 2016年8月24日 Group : Source and taxonomy改定 1.4 2023年11月8日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_oper_list Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_oper_list.symmetry_operation
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