Entry Database : PDB / ID : 5ho4 Structure visualization Downloads & linksTitle Crystal structure of hnRNPA2B1 in complex with 10-mer RNA ComponentsHeterogeneous nuclear ribonucleoproteins A2/B1 RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*AP*GP*C)-3') DetailsKeywords RNA BINDING PROTEIN/RNA / hnRNPA2B1 / RRMs / RNA BINDING PROTEIN-RNA complexFunction / homology Function and homology informationFunction Domain/homology Component
: / miRNA transport / positive regulation of telomere maintenance via telomere lengthening / RNA transport / G-quadruplex DNA unwinding / primary miRNA processing / single-stranded telomeric DNA binding / N6-methyladenosine-containing RNA reader activity / G-rich strand telomeric DNA binding / miRNA binding ... : / miRNA transport / positive regulation of telomere maintenance via telomere lengthening / RNA transport / G-quadruplex DNA unwinding / primary miRNA processing / single-stranded telomeric DNA binding / N6-methyladenosine-containing RNA reader activity / G-rich strand telomeric DNA binding / miRNA binding / negative regulation of mRNA splicing, via spliceosome / Processing of Capped Intron-Containing Pre-mRNA / mRNA transport / mRNA export from nucleus / Cajal body / pre-mRNA intronic binding / Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation / catalytic step 2 spliceosome / mRNA Splicing - Major Pathway / molecular condensate scaffold activity / mRNA 3'-UTR binding / spliceosomal complex / nuclear matrix / mRNA splicing, via spliceosome / mRNA processing / chromosome, telomeric region / ribonucleoprotein complex / negative regulation of transcription by RNA polymerase II / RNA binding / extracellular exosome / nucleoplasm / identical protein binding / membrane / nucleus / cytoplasm Similarity search - Function hnRNP A2/B1, RNA recognition motif 1 / Heterogeneous nuclear ribonucleoprotein A1/A2, C-terminal / Heterogeneous nuclear ribonucleoprotein A1, LC domain / RRM (RNA recognition motif) domain / RNA recognition motif / RNA recognition motif / Eukaryotic RNA Recognition Motif (RRM) profile. / RNA recognition motif domain / RNA-binding domain superfamily / Nucleotide-binding alpha-beta plait domain superfamily ... hnRNP A2/B1, RNA recognition motif 1 / Heterogeneous nuclear ribonucleoprotein A1/A2, C-terminal / Heterogeneous nuclear ribonucleoprotein A1, LC domain / RRM (RNA recognition motif) domain / RNA recognition motif / RNA recognition motif / Eukaryotic RNA Recognition Motif (RRM) profile. / RNA recognition motif domain / RNA-binding domain superfamily / Nucleotide-binding alpha-beta plait domain superfamily / Alpha-Beta Plaits / 2-Layer Sandwich / Alpha Beta Similarity search - Domain/homologyBiological species Homo sapiens (human)synthetic construct (others) Method X-RAY DIFFRACTION / SYNCHROTRON / Resolution : 1.85 Å DetailsAuthors Wu, B.X. / Su, S.C. / Gan, J.H. / Ma, J.B. CitationJournal : Nat Commun / Year : 2018Title : Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.Authors : Wu, B.X. / Su, S.C. / Patil, D.P. / Liu, H. / Gan, J.H. / Jaffrey, S.R. / Ma, J.B. History Deposition Jan 19, 2016 Deposition site : RCSB / Processing site : PDBJRevision 1.0 Feb 8, 2017 Provider : repository / Type : Initial releaseRevision 1.1 Mar 1, 2017 Group : Structure summaryRevision 1.2 Feb 7, 2018 Group : Database references / Category : citation / citation_authorItem : _citation.country / _citation.journal_abbrev ... _citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.pdbx_database_id_DOI / _citation.title / _citation.year Revision 1.3 May 22, 2019 Group : Data collection / Database references / Structure summaryCategory : citation / citation_author / structItem : _citation.page_first / _citation.page_last ... _citation.page_first / _citation.page_last / _citation.pdbx_database_id_PubMed / _citation.title / _citation_author.identifier_ORCID / _struct.title Revision 1.4 Mar 20, 2024 Group : Data collection / Database references / Category : chem_comp_atom / chem_comp_bond / database_2Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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