Entry Database : PDB / ID : 5hm2 Structure visualization Downloads & linksTitle Crystal structure of the 3C protease from South African Territories type 2 foot-and-mouth disease virus Components3C proteinase Details Keywords HYDROLASE / picornavirus / 3C protease / trypsin-like proteaseFunction / homology Function and homology informationFunction Domain/homology Component
RNA-protein covalent cross-linking / virion component => GO:0044423 / viral capsid / host cell cytoplasm / RNA helicase activity / viral RNA genome replication / cysteine-type endopeptidase activity / RNA-dependent RNA polymerase activity / DNA-templated transcription / RNA binding ... RNA-protein covalent cross-linking / virion component => GO:0044423 / viral capsid / host cell cytoplasm / RNA helicase activity / viral RNA genome replication / cysteine-type endopeptidase activity / RNA-dependent RNA polymerase activity / DNA-templated transcription / RNA binding / ATP binding / cytoplasm Similarity search - Function Helicase/polymerase/peptidase polyprotein, Calicivirus-type / Picornavirales 3C/3C-like protease domain / Picornavirales 3C/3C-like protease domain profile. / Peptidase C3A/C3B, picornaviral / 3C cysteine protease (picornain 3C) / Helicase, superfamily 3, single-stranded RNA virus / Superfamily 3 helicase of positive ssRNA viruses domain profile. / Helicase, superfamily 3, single-stranded DNA/RNA virus / RNA helicase / Trypsin-like serine proteases ... Helicase/polymerase/peptidase polyprotein, Calicivirus-type / Picornavirales 3C/3C-like protease domain / Picornavirales 3C/3C-like protease domain profile. / Peptidase C3A/C3B, picornaviral / 3C cysteine protease (picornain 3C) / Helicase, superfamily 3, single-stranded RNA virus / Superfamily 3 helicase of positive ssRNA viruses domain profile. / Helicase, superfamily 3, single-stranded DNA/RNA virus / RNA helicase / Trypsin-like serine proteases / Thrombin, subunit H / RNA-directed RNA polymerase, C-terminal domain / Viral RNA-dependent RNA polymerase / Reverse transcriptase/Diguanylate cyclase domain / RNA-directed RNA polymerase, catalytic domain / RdRp of positive ssRNA viruses catalytic domain profile. / Peptidase S1, PA clan, chymotrypsin-like fold / Peptidase S1, PA clan / DNA/RNA polymerase superfamily / Beta Barrel / P-loop containing nucleoside triphosphate hydrolase / Mainly Beta Similarity search - Domain/homologyBiological species Foot-and-mouth disease virus - type SAT 2Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 3.2 Å DetailsAuthors Yang, J. / Leen, E.N. / Curry, S. Funding support United Kingdom, 1items Details Hide detailsOrganization Grant number Country Wellcome Trust TBD United Kingdom
CitationJournal : Peerj / Year : 2016Title : Crystal structure of the 3C protease from Southern African Territories type 2 foot-and-mouth disease virus.Authors : Yang, J. / Leen, E.N. / Maree, F.F. / Curry, S. History Deposition Jan 15, 2016 Deposition site : RCSB / Processing site : PDBERevision 1.0 Mar 2, 2016 Provider : repository / Type : Initial releaseRevision 1.1 May 11, 2016 Group : Database referencesRevision 1.2 May 25, 2016 Group : Database referencesRevision 1.3 Jan 10, 2024 Group : Data collection / Database references / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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