Entry | Database: PDB / ID: 5hgq |
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Title | Loa loa Lysyl-tRNA synthetase in complex with Cladosporin. |
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Components | Lysine--tRNA ligase |
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Keywords | LIGASE/LIGASE INHIBITOR / Cladosporin / Lysine-tRNA synthetase / Loa loa / helminth parasites / LIGASE-LIGASE INHIBITOR complex |
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Function / homology | Function and homology information
Bira Bifunctional Protein; Domain 2 / BirA Bifunctional Protein; domain 2 / Nucleic acid-binding proteins / OB fold (Dihydrolipoamide Acetyltransferase, E2P) / Beta Barrel / 2-Layer Sandwich / Mainly Beta / Alpha BetaSimilarity search - Domain/homology |
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Biological species | Loa loa (African eye worm) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.283 Å |
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Authors | Sharma, A. / Sharma, M. / Yogavel, M. / Sharma, A. |
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Funding support | India, 1items Organization | Grant number | Country |
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| | India |
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Citation | Journal: PLoS Negl Trop Dis / Year: 2016 Title: Protein Translation Enzyme lysyl-tRNA Synthetase Presents a New Target for Drug Development against Causative Agents of Loiasis and Schistosomiasis Authors: Sharma, A. / Sharma, M. / Yogavel, M. / Sharma, A. |
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History | Deposition | Jan 8, 2016 | Deposition site: RCSB / Processing site: PDBJ |
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Revision 1.0 | Oct 26, 2016 | Provider: repository / Type: Initial release |
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Revision 1.1 | Aug 23, 2017 | Group: Database references / Derived calculations / Category: citation / pdbx_struct_oper_list Item: _citation.journal_abbrev / _citation.journal_volume ..._citation.journal_abbrev / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_PubMed / _citation.title / _pdbx_struct_oper_list.symmetry_operation |
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Revision 1.2 | Nov 8, 2023 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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