Entry | Database: PDB / ID: 5h0v |
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Title | Crystal structure of H88A mutated human transthyretin |
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Components | Transthyretin |
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Keywords | TRANSPORT PROTEIN / transthhyretin / amyloidosis / transporter |
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Function / homology | Function and homology information
Retinoid cycle disease events / The canonical retinoid cycle in rods (twilight vision) / thyroid hormone binding / purine nucleobase metabolic process / Non-integrin membrane-ECM interactions / Retinoid metabolism and transport / hormone activity / azurophil granule lumen / Amyloid fiber formation / Neutrophil degranulation ...Retinoid cycle disease events / The canonical retinoid cycle in rods (twilight vision) / thyroid hormone binding / purine nucleobase metabolic process / Non-integrin membrane-ECM interactions / Retinoid metabolism and transport / hormone activity / azurophil granule lumen / Amyloid fiber formation / Neutrophil degranulation / extracellular space / extracellular exosome / extracellular region / identical protein bindingSimilarity search - Function Transthyretin, conserved site / Transthyretin signature 2. / Transthyretin, thyroxine binding site / Transthyretin signature 1. / Transthyretin / Transthyretin/hydroxyisourate hydrolase / Transthyretin/hydroxyisourate hydrolase domain / Transthyretin/hydroxyisourate hydrolase domain superfamily / HIUase/Transthyretin familySimilarity search - Domain/homology |
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Biological species | Homo sapiens (human) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / Resolution: 1.58 Å |
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Authors | Yokoyama, T. / Hanawa, Y. / Obita, T. / Mizuguchi, M. |
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Citation | Journal: FEBS Lett. / Year: 2017 Title: Stability and crystal structures of His88 mutant human transthyretins Authors: Yokoyama, T. / Hanawa, Y. / Obita, T. / Mizuguchi, M. |
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History | Deposition | Oct 7, 2016 | Deposition site: PDBJ / Processing site: PDBJ |
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Revision 1.0 | Jun 14, 2017 | Provider: repository / Type: Initial release |
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Revision 1.1 | Jul 26, 2017 | Group: Database references / Category: citation Item: _citation.journal_volume / _citation.page_first ..._citation.journal_volume / _citation.page_first / _citation.page_last / _citation.title |
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Revision 1.2 | Mar 20, 2024 | Group: Data collection / Database references / Derived calculations Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_struct_conn_angle / struct_conn Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr2_auth_seq_id |
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