登録情報 データベース : PDB / ID : 5gs5 構造の表示 ダウンロードとリンクタイトル Crystal structure of apo rat STING 要素Stimulator of interferon genes protein 詳細 キーワード IMMUNE SYSTEM / rat STING機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
STING mediated induction of host immune responses / STAT6-mediated induction of chemokines / IRF3-mediated induction of type I IFN / Regulation of innate immune responses to cytosolic DNA / : / STING complex / protein localization to endoplasmic reticulum / 2',3'-cyclic GMP-AMP binding / cyclic-di-GMP binding / positive regulation of type I interferon-mediated signaling pathway ... STING mediated induction of host immune responses / STAT6-mediated induction of chemokines / IRF3-mediated induction of type I IFN / Regulation of innate immune responses to cytosolic DNA / : / STING complex / protein localization to endoplasmic reticulum / 2',3'-cyclic GMP-AMP binding / cyclic-di-GMP binding / positive regulation of type I interferon-mediated signaling pathway / proton channel activity / cGAS/STING signaling pathway / pattern recognition receptor signaling pathway / reticulophagy / Neutrophil degranulation / cytoplasmic pattern recognition receptor signaling pathway / cellular response to exogenous dsRNA / protein complex oligomerization / autophagosome membrane / positive regulation of macroautophagy / autophagosome assembly / positive regulation of type I interferon production / cellular response to interferon-beta / positive regulation of defense response to virus by host / signaling adaptor activity / endoplasmic reticulum-Golgi intermediate compartment membrane / antiviral innate immune response / activation of innate immune response / autophagosome / positive regulation of interferon-beta production / peroxisome / regulation of gene expression / regulation of inflammatory response / defense response to virus / mitochondrial outer membrane / RNA polymerase II-specific DNA-binding transcription factor binding / endosome / Golgi membrane / innate immune response / ubiquitin protein ligase binding / endoplasmic reticulum membrane / protein kinase binding / perinuclear region of cytoplasm / endoplasmic reticulum / Golgi apparatus / protein homodimerization activity / positive regulation of transcription by RNA polymerase II / identical protein binding / plasma membrane / cytoplasm 類似検索 - 分子機能 Stimulator of interferon genes protein / : / STING transmembrane domain / : / : / Stimulator of interferon genes protein / Stimulator of interferon genes protein, C-terminal domain superfamily / STING ligand-binding domain / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta 類似検索 - ドメイン・相同性生物種 Rattus norvegicus (ドブネズミ)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.84 Å 詳細データ登録者 Zhang, H. / Han, M.J. / Tao, J.L. / Ye, Z.Y. / Du, X.X. / Deng, M.J. / Zhang, X.Y. / Li, L.F. / Jiang, Z.F. / Su, X.D. 引用ジャーナル : To Be Published タイトル : Crystal structure of apo ratSTING
著者 :
Zhang, H. / Han, M.J. / Tao, J.L. / Ye, Z.Y. / Du, X.X. / Deng, M.J. / Zhang, X.Y. / Li, L.F. / Jiang, Z.F. / Su, X.D. 残り1件を表示 表示を減らす#1: ジャーナル : Sci Rep. / 年 : 2015タイトル : Rat and human STINGs profile similarly towards anticancer/antiviral compounds
著者 :
Zhang, H. / Han, M.J. / Tao, J.L. / Ye, Z.Y. / Du, X.X. / Deng, M.J. / Zhang, X.Y. / Li, L.F. / Jiang, Z.F. / Su, X.D. 履歴 登録 2016年8月13日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2017年10月25日 Provider : repository / タイプ : Initial release改定 1.1 2023年11月8日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ncs_dom_lim Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id 改定 1.2 2024年10月23日 Group : Structure summaryカテゴリ : pdbx_entry_details / pdbx_modification_feature
すべて表示 表示を減らす