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- PDB-5g10: Pseudomonas aeruginosa HDAH bound to 9,9,9 trifluoro-8,8-dihydroy... -
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Open data
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Basic information
Entry | Database: PDB / ID: 5g10 | ||||||
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Title | Pseudomonas aeruginosa HDAH bound to 9,9,9 trifluoro-8,8-dihydroy-N-phenylnonanamide | ||||||
![]() | HDAH | ||||||
![]() | HYDROLASE / HDAH / HDAC / HDLP | ||||||
Function / homology | ![]() Hydrolases; Acting on carbon-nitrogen bonds, other than peptide bonds; In linear amides / histone deacetylase activity / hydrolase activity / negative regulation of transcription by RNA polymerase II / metal ion binding / cytoplasm Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Kraemer, A. / Meyer-Almes, F.J. / Yildiz, O. | ||||||
![]() | ![]() Title: Crystal Structure of a Histone Deacetylase Homologue from Pseudomonas aeruginosa. Authors: Kramer, A. / Wagner, T. / Yildiz, O. / Meyer-Almes, F.J. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 317.7 KB | Display | ![]() |
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PDB format | ![]() | 260 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 893.8 KB | Display | ![]() |
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Full document | ![]() | 907.7 KB | Display | |
Data in XML | ![]() | 34.9 KB | Display | |
Data in CIF | ![]() | 52.2 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 5g0xSC ![]() 5g0yC ![]() 5g11C ![]() 5g12C ![]() 5g13C ![]() 5g14 S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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Unit cell |
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Components
#1: Protein | Mass: 40967.242 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() #2: Chemical | #3: Chemical | ChemComp-K / #4: Chemical | #5: Water | ChemComp-HOH / | |
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-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.09 Å3/Da / Density % sol: 47 % / Description: NONE |
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Crystal grow | pH: 7.5 / Details: pH 7.5 |
-Data collection
Diffraction | Mean temperature: 100 K |
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Diffraction source | Source: ![]() ![]() ![]() |
Detector | Type: DECTRIS PILATUS 6M / Detector: PIXEL / Date: Dec 18, 2014 |
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 0.97902 Å / Relative weight: 1 |
Reflection | Resolution: 1.71→75.94 Å / Num. obs: 75585 / % possible obs: 99.3 % / Observed criterion σ(I): 2.1 / Redundancy: 7.7 % / Rmerge(I) obs: 0.15 / Net I/σ(I): 8.2 |
Reflection shell | Resolution: 1.71→1.75 Å / Redundancy: 8 % / Rmerge(I) obs: 1.18 / Mean I/σ(I) obs: 2.1 / % possible all: 100 |
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Processing
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Refinement | Method to determine structure: ![]() Starting model: PDB ENTRY 5G0X Resolution: 1.71→75.94 Å / Cor.coef. Fo:Fc: 0.968 / Cor.coef. Fo:Fc free: 0.958 / SU B: 5.348 / SU ML: 0.076 / Cross valid method: THROUGHOUT / ESU R: 0.182 / ESU R Free: 0.101 / Stereochemistry target values: MAXIMUM LIKELIHOOD / Details: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS.
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Solvent computation | Ion probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.2 Å / Solvent model: MASK | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | Biso mean: 20.653 Å2
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Refinement step | Cycle: LAST / Resolution: 1.71→75.94 Å
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Refine LS restraints |
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