Entry Database : PDB / ID : 5e9v Structure visualization Downloads & linksTitle Crystal structure of BRD9 bromodomain in complex with an indolizine ligand ComponentsBromodomain-containing protein 9 Details Keywords TRANSCRIPTION / Bromodomain / chromatin regulationFunction / homology Function and homology informationFunction Domain/homology Component
GBAF complex / SWI/SNF complex / positive regulation of stem cell population maintenance / negative regulation of cell differentiation / lysine-acetylated histone binding / nucleic acid binding / chromatin remodeling / positive regulation of cell population proliferation / chromatin / regulation of transcription by RNA polymerase II ... GBAF complex / SWI/SNF complex / positive regulation of stem cell population maintenance / negative regulation of cell differentiation / lysine-acetylated histone binding / nucleic acid binding / chromatin remodeling / positive regulation of cell population proliferation / chromatin / regulation of transcription by RNA polymerase II / nucleoplasm / nucleus Similarity search - Function Protein of unknown function DUF3512 / Domain of unknown function (DUF3512) / Bromodomain-like / Histone Acetyltransferase; Chain A / Bromodomain / Bromodomain profile. / bromo domain / Bromodomain / Bromodomain-like superfamily / Up-down Bundle / Mainly Alpha Similarity search - Domain/homologyBiological species Homo sapiens (human)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.8 Å DetailsAuthors Tallant, C. / Hay, D.A. / Krojer, T. / Nunez-Alonso, G. / Picaud, S. / Fedorov, O. / Schofield, C.J. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. ...Tallant, C. / Hay, D.A. / Krojer, T. / Nunez-Alonso, G. / Picaud, S. / Fedorov, O. / Schofield, C.J. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Bountra, C. / Brennan, P.E. / Knapp, S. CitationJournal : To Be Published Title : Crystal structure of BRD9 bromodomain in complex with an indolizine ligandAuthors : Tallant, C. / Hay, D.A. / Krojer, T. / Nunez-Alonso, G. / Picaud, S. / Fedorov, O. / Schofield, C.J. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Bountra, C. / Brennan, P.E. / Knapp, S. History Deposition Oct 15, 2015 Deposition site : RCSB / Processing site : PDBERevision 1.0 Oct 28, 2015 Provider : repository / Type : Initial releaseRevision 1.1 Jan 10, 2024 Group : Data collection / Database references / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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