Entry Database : PDB / ID : 5e0e Structure visualization Downloads & linksTitle Crystal Structure of Cytochrome P450 2B37 from Desert Woodrat in complex with 4-(4-chlorophenyl)imidazole ComponentsCytochrome P450 family 2 subfamily B Details Keywords Oxidoreductase/Oxidoreductase inhibitor / Cytochrome P450 / CYP2B37 / 4-(4-chlorophenyl)imidazole / Inhibitor / Oxidoreductase-Oxidoreductase inhibitor complexFunction / homology Function and homology informationFunction Domain/homology Component
Cytochrome P450, E-class, group I, CYP2B-like / Cytochrome P450, E-class, group I / Cytochrome p450 / Cytochrome P450 / Cytochrome P450, conserved site / Cytochrome P450 cysteine heme-iron ligand signature. / Cytochrome P450 / Cytochrome P450 superfamily / Cytochrome P450 / Orthogonal Bundle / Mainly Alpha Similarity search - Domain/homologyBiological species Neotoma lepida (desert woodrat)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 3.4 Å DetailsAuthors Shah, M.B. / Halpert, J.R. / Stout, C.D. Funding support United States, 1items Details Hide detailsOrganization Grant number Country National Science Foundation (NSF, United States) IOS 1256840 United States
CitationJournal : Mol.Pharmacol. / Year : 2016Title : Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism.Authors : Shah, M.B. / Liu, J. / Huo, L. / Zhang, Q. / Dearing, M.D. / Wilderman, P.R. / Szklarz, G.D. / Stout, C.D. / Halpert, J.R. History Deposition Sep 28, 2015 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Feb 10, 2016 Provider : repository / Type : Initial releaseRevision 1.1 Mar 23, 2016 Group : Database referencesRevision 1.2 Sep 13, 2017 Group : Author supporting evidence / Database references / Derived calculationsCategory : citation / pdbx_audit_support / pdbx_struct_oper_listItem : _citation.journal_id_CSD / _pdbx_audit_support.funding_organization / _pdbx_struct_oper_list.symmetry_operationRevision 1.3 Nov 27, 2019 Group : Author supporting evidence / Category : pdbx_audit_support / Item : _pdbx_audit_support.funding_organizationRevision 1.4 Sep 27, 2023 Group : Data collection / Database references / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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