Entry | Database: PDB / ID: 5dwz |
---|
Title | Structural and functional characterization of PqsBC, a condensing enzyme in the biosynthesis of the Pseudomonas aeruginosa quinolone signal |
---|
Components | - 3-oxoacyl-(Acyl carrier protein) synthase III
- 3-oxoacyl-[acyl-carrier-protein] synthase 3
|
---|
Keywords | TRANSFERASE / PROTEIN COMPLEX / PqsB / PqsC |
---|
Function / homology | Function and homology information
2-heptyl-4(1H)-quinolone synthase / beta-ketoacyl-[acyl-carrier-protein] synthase III / beta-ketoacyl-acyl-carrier-protein synthase III activity / secondary metabolite biosynthetic process / acyltransferase activity / 3-oxoacyl-[acyl-carrier-protein] synthase activity / fatty acid biosynthetic process / cytoplasmSimilarity search - Function 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III / 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III / 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal / 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal / Thiolase/Chalcone synthase / Peroxisomal Thiolase; Chain A, domain 1 / Thiolase-like / 3-Layer(aba) Sandwich / Alpha BetaSimilarity search - Domain/homology DI(HYDROXYETHYL)ETHER / TRIETHYLENE GLYCOL / PHOSPHATE ION / 3-oxoacyl-(Acyl carrier protein) synthase III / 3-oxoacyl-ACP synthase III family protein / 2-heptyl-4(1H)-quinolone synthase subunit PqsC / 2-heptyl-4(1H)-quinolone synthase subunit PqsBSimilarity search - Component |
---|
Biological species | ![](img/tx_bacteria.gif) Pseudomonas aeruginosa (bacteria) |
---|
Method | X-RAY DIFFRACTION / SYNCHROTRON / SIRAS / Resolution: 2.04 Å |
---|
Authors | Drees, S.L. / Li, C. / Prasetya, F. / Saleem, M. / Dreveny, I. / Hennecke, U. / Williams, P. / Emsley, J. / Fetzner, S. |
---|
Funding support | Germany, 1items Organization | Grant number | Country |
---|
German Research Foundation | FE 383/23-1 | Germany |
|
---|
Citation | Journal: J.Biol.Chem. / Year: 2016 Title: PqsBC, a Condensing Enzyme in the Biosynthesis of the Pseudomonas aeruginosa Quinolone Signal: CRYSTAL STRUCTURE, INHIBITION, AND REACTION MECHANISM. Authors: Drees, S.L. / Li, C. / Prasetya, F. / Saleem, M. / Dreveny, I. / Williams, P. / Hennecke, U. / Emsley, J. / Fetzner, S. |
---|
History | Deposition | Sep 23, 2015 | Deposition site: RCSB / Processing site: PDBE |
---|
Revision 1.0 | Feb 3, 2016 | Provider: repository / Type: Initial release |
---|
Revision 1.1 | Feb 10, 2016 | Group: Database references |
---|
Revision 1.2 | Apr 6, 2016 | Group: Database references |
---|
Revision 1.3 | May 11, 2016 | Group: Source and taxonomy |
---|
Revision 1.4 | Sep 6, 2017 | Group: Advisory / Author supporting evidence / Category: pdbx_audit_support / pdbx_unobs_or_zero_occ_atoms / Item: _pdbx_audit_support.funding_organization |
---|
Revision 1.5 | May 8, 2024 | Group: Advisory / Data collection ...Advisory / Data collection / Database references / Derived calculations Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_struct_conn_angle / pdbx_unobs_or_zero_occ_atoms / struct_conn Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr2_auth_seq_id |
---|
|
---|