登録情報 | データベース: PDB / ID: 5dti |
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タイトル | Crystal structure of mouse acetylcholinesterase |
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要素 | Acetylcholinesterase |
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キーワード | HYDROLASE |
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機能・相同性 | 機能・相同性情報
acetylcholine metabolic process / serine hydrolase activity / choline binding / acetylcholine catabolic process / acetylcholine binding / acetylcholinesterase / positive regulation of dendrite morphogenesis / acetylcholine receptor signaling pathway / choline metabolic process / osteoblast development ...acetylcholine metabolic process / serine hydrolase activity / choline binding / acetylcholine catabolic process / acetylcholine binding / acetylcholinesterase / positive regulation of dendrite morphogenesis / acetylcholine receptor signaling pathway / choline metabolic process / osteoblast development / acetylcholinesterase activity / positive regulation of axonogenesis / basement membrane / regulation of receptor recycling / side of membrane / synaptic cleft / laminin binding / collagen binding / synapse assembly / response to insulin / neuromuscular junction / receptor internalization / nuclear envelope / retina development in camera-type eye / presynaptic membrane / positive regulation of cold-induced thermogenesis / postsynaptic membrane / cell adhesion / endoplasmic reticulum lumen / axon / neuronal cell body / synapse / dendrite / perinuclear region of cytoplasm / Golgi apparatus / cell surface / protein homodimerization activity / extracellular space / identical protein binding / plasma membrane類似検索 - 分子機能 Acetylcholinesterase, tetramerisation domain / Acetylcholinesterase tetramerisation domain / : / Cholinesterase / Carboxylesterase type B, conserved site / Carboxylesterases type-B signature 2. / Carboxylesterase type B, active site / Carboxylesterases type-B serine active site. / Carboxylesterase, type B / Carboxylesterase family ...Acetylcholinesterase, tetramerisation domain / Acetylcholinesterase tetramerisation domain / : / Cholinesterase / Carboxylesterase type B, conserved site / Carboxylesterases type-B signature 2. / Carboxylesterase type B, active site / Carboxylesterases type-B serine active site. / Carboxylesterase, type B / Carboxylesterase family / Alpha/Beta hydrolase fold, catalytic domain / Alpha/Beta hydrolase fold / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | ![](img/tx_mammal.gif) Mus musculus (ハツカネズミ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.003 Å |
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データ登録者 | Tran, T.H. / Tong, L. |
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引用 | ジャーナル: Chembiochem / 年: 2015 タイトル: Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates. 著者: Katz, F.S. / Pecic, S. / Tran, T.H. / Trakht, I. / Schneider, L. / Zhu, Z. / Ton-That, L. / Luzac, M. / Zlatanic, V. / Damera, S. / Macdonald, J. / Landry, D.W. / Tong, L. / Stojanovic, M.N. |
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履歴 | 登録 | 2015年9月18日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2015年10月21日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2015年11月4日 | Group: Source and taxonomy |
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改定 1.2 | 2023年9月27日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_oper_list Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_oper_list.symmetry_operation |
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