登録情報 データベース : PDB / ID : 5diy 構造の表示 ダウンロードとリンクタイトル Thermobaculum terrenum O-GlcNAc hydrolase mutant - D120N 要素Hyaluronidase TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 詳細キーワード HYDROLASE / GH84 / OGA / O-GlcNAc hydrolase / O-GlcNAcase機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
hexosaminidase activity / carbohydrate derivative metabolic process / cardiac septum development / positive regulation of cGAS/STING signaling pathway / coronary vasculature development / non-canonical NF-kappaB signal transduction / aorta development / mitogen-activated protein kinase p38 binding / protein serine/threonine phosphatase activity / heart morphogenesis ... hexosaminidase activity / carbohydrate derivative metabolic process / cardiac septum development / positive regulation of cGAS/STING signaling pathway / coronary vasculature development / non-canonical NF-kappaB signal transduction / aorta development / mitogen-activated protein kinase p38 binding / protein serine/threonine phosphatase activity / heart morphogenesis / IRAK2 mediated activation of TAK1 complex / Alpha-protein kinase 1 signaling pathway / IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation / TICAM1,TRAF6-dependent induction of TAK1 complex / TRAF6-mediated induction of TAK1 complex within TLR4 complex / transforming growth factor beta receptor signaling pathway / protein serine/threonine kinase activator activity / JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 / TNFR1-induced NF-kappa-B signaling pathway / activated TAK1 mediates p38 MAPK activation / lung development / TAK1-dependent IKK and NF-kappa-B activation / NOD1/2 Signaling Pathway / CLEC7A (Dectin-1) signaling / FCERI mediated NF-kB activation / Interleukin-1 signaling / molecular adaptor activity / in utero embryonic development / positive regulation of MAPK cascade / endosome membrane / Ub-specific processing proteases / endoplasmic reticulum membrane / protein-containing complex binding / SARS-CoV-2 activates/modulates innate and adaptive immune responses / endoplasmic reticulum / signal transduction / protein-containing complex / cytosol / cytoplasm 類似検索 - 分子機能 Beta-N-acetylglucosaminidase / beta-N-acetylglucosaminidase / Glycosyl hydrolases family 84 (GH84) domain profile. / : / Protein phosphatase 2C / Protein phosphatase 2C family / Serine/threonine phosphatases, family 2C, catalytic domain / PPM-type phosphatase domain profile. / PPM-type phosphatase-like domain / PPM-type phosphatase-like domain superfamily ... Beta-N-acetylglucosaminidase / beta-N-acetylglucosaminidase / Glycosyl hydrolases family 84 (GH84) domain profile. / : / Protein phosphatase 2C / Protein phosphatase 2C family / Serine/threonine phosphatases, family 2C, catalytic domain / PPM-type phosphatase domain profile. / PPM-type phosphatase-like domain / PPM-type phosphatase-like domain superfamily / Glycosidases / Glycoside hydrolase superfamily / TIM Barrel / Alpha-Beta Barrel / Alpha Beta 類似検索 - ドメイン・相同性 Hyaluronidase / TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 類似検索 - 構成要素生物種 Thermobaculum terrenum (バクテリア)Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 解像度 : 2.06 Å 詳細データ登録者 Ostrowski, A. / Gundogdu, M. / Ferenbach, A.T. / Lebedev, A. / van Aalten, D.M.F. 資金援助 英国, 1件 詳細 詳細を隠す組織 認可番号 国 Wellcome Trust WT087590MA 英国
引用ジャーナル : J.Biol.Chem. / 年 : 2015タイトル : Evidence for a Functional O-Linked N-Acetylglucosamine (O-GlcNAc) System in the Thermophilic Bacterium Thermobaculum terrenum.著者 : Ostrowski, A. / Gundogdu, M. / Ferenbach, A.T. / Lebedev, A.A. / van Aalten, D.M. 履歴 登録 2015年9月1日 登録サイト : RCSB / 処理サイト : PDBE改定 1.0 2015年10月28日 Provider : repository / タイプ : Initial release改定 1.1 2015年11月4日 Group : Database references改定 1.2 2015年12月30日 Group : Database references改定 2.0 2017年8月30日 Group : Advisory / Atomic model / Author supporting evidenceカテゴリ : atom_site / pdbx_audit_support / pdbx_unobs_or_zero_occ_atomsItem : _atom_site.B_iso_or_equiv / _atom_site.Cartn_x ... _atom_site.B_iso_or_equiv / _atom_site.Cartn_x / _atom_site.Cartn_y / _atom_site.Cartn_z / _pdbx_audit_support.funding_organization 改定 2.1 2020年7月29日 Group : Data collection / Derived calculations / Structure summaryカテゴリ : chem_comp / entity ... chem_comp / entity / pdbx_chem_comp_identifier / pdbx_entity_nonpoly / struct_conn / struct_site / struct_site_gen Item : _chem_comp.name / _chem_comp.type ... _chem_comp.name / _chem_comp.type / _entity.pdbx_description / _pdbx_entity_nonpoly.name / _struct_conn.pdbx_role 解説 : Carbohydrate remediation / Provider : repository / タイプ : Remediation改定 2.2 2024年10月23日 Group : Advisory / Data collection ... Advisory / Data collection / Database references / Structure summary カテゴリ : chem_comp / chem_comp_atom ... chem_comp / chem_comp_atom / chem_comp_bond / database_2 / pdbx_entry_details / pdbx_modification_feature / pdbx_unobs_or_zero_occ_atoms Item : _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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