Entry Database : PDB / ID : 5ddz Structure visualization Downloads & linksTitle Crystal structure of the RTA-c10-P2 complex Components60S acidic ribosomal protein P2 Ricin DetailsKeywords HYDROLASE/PEPTIDE / Ricin / P2 / Complex / HYDROLASE-PEPTIDE complexFunction / homology Function and homology informationFunction Domain/homology Component
cytoplasmic translational elongation / rRNA N-glycosylase / rRNA N-glycosylase activity / AMP binding / Peptide chain elongation / Selenocysteine synthesis / Formation of a pool of free 40S subunits / Eukaryotic Translation Termination / Response of EIF2AK4 (GCN2) to amino acid deficiency / SRP-dependent cotranslational protein targeting to membrane ... cytoplasmic translational elongation / rRNA N-glycosylase / rRNA N-glycosylase activity / AMP binding / Peptide chain elongation / Selenocysteine synthesis / Formation of a pool of free 40S subunits / Eukaryotic Translation Termination / Response of EIF2AK4 (GCN2) to amino acid deficiency / SRP-dependent cotranslational protein targeting to membrane / Viral mRNA Translation / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / GTP hydrolysis and joining of the 60S ribosomal subunit / L13a-mediated translational silencing of Ceruloplasmin expression / Major pathway of rRNA processing in the nucleolus and cytosol / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / defense response / Regulation of expression of SLITs and ROBOs / toxin activity / carbohydrate binding / killing of cells of another organism / cytosolic large ribosomal subunit / cytoplasmic translation / negative regulation of translation / structural constituent of ribosome / translation / focal adhesion / extracellular exosome / membrane / cytosol / cytoplasm Similarity search - Function Ribosomal protein P2 / Ribosomal protein L12/P1/P2 family / Ribosomal protein P1/P2, N-terminal domain / 60s Acidic ribosomal protein / Ricin (A Subunit), domain 2 / Ricin (A Subunit), domain 2 / Ricin (A subunit); domain 1 / Ricin (A subunit), domain 1 / Ribosome-inactivating protein conserved site / Shiga/ricin ribosomal inactivating toxins active site signature. ... Ribosomal protein P2 / Ribosomal protein L12/P1/P2 family / Ribosomal protein P1/P2, N-terminal domain / 60s Acidic ribosomal protein / Ricin (A Subunit), domain 2 / Ricin (A Subunit), domain 2 / Ricin (A subunit); domain 1 / Ricin (A subunit), domain 1 / Ribosome-inactivating protein conserved site / Shiga/ricin ribosomal inactivating toxins active site signature. / Ricin-type beta-trefoil lectin domain / Ribosome-inactivating protein type 1/2 / Ribosome-inactivating protein / Ribosome-inactivating protein, subdomain 1 / Ribosome-inactivating protein, subdomain 2 / Ribosome-inactivating protein superfamily / Ribosome inactivating protein / Ricin-type beta-trefoil / Lectin domain of ricin B chain profile. / Ricin B, lectin domain / Ricin B-like lectins / Few Secondary Structures / Irregular / 3-Layer(aba) Sandwich / Alpha Beta Similarity search - Domain/homologyBiological species Ricinus communis (castor bean)Homo sapiens (human)Method X-RAY DIFFRACTION / MOLECULAR REPLACEMENT / Resolution : 1.5 Å DetailsAuthors Zhu, Y. / Fan, X. / Wang, C. / Niu, L. / Li, X. / Teng, M. CitationJournal : Sci Rep / Year : 2016Title : Structural insights into the interaction of the ribosomal P stalk protein P2 with a type II ribosome-inactivating protein ricinAuthors : Fan, X. / Zhu, Y. / Wang, C. / Niu, L. / Teng, M. / Li, X. History Deposition Aug 25, 2015 Deposition site : RCSB / Processing site : PDBJRevision 1.0 Sep 7, 2016 Provider : repository / Type : Initial releaseRevision 1.1 Dec 28, 2016 Group : Database referencesRevision 1.2 Nov 8, 2023 Group : Data collection / Database references / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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