登録情報 データベース : PDB / ID : 5bnw 構造の表示 ダウンロードとリンクタイトル The active site of O-GlcNAc transferase imposes constraints on substrate sequence 要素UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit laminB1 residues 179-191 詳細キーワード TRANSFERASE / o-glcnac transferase / glycosyl transferase機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
negative regulation of non-canonical inflammasome complex assembly / protein N-acetylglucosaminyltransferase complex / regulation of insulin receptor signaling pathway / protein O-acetylglucosaminyltransferase activity / protein O-GlcNAc transferase / positive regulation of transcription from RNA polymerase II promoter by glucose / nuclear envelope organization / acetylglucosaminyltransferase activity / nuclear pore localization / regulation of Rac protein signal transduction ... negative regulation of non-canonical inflammasome complex assembly / protein N-acetylglucosaminyltransferase complex / regulation of insulin receptor signaling pathway / protein O-acetylglucosaminyltransferase activity / protein O-GlcNAc transferase / positive regulation of transcription from RNA polymerase II promoter by glucose / nuclear envelope organization / acetylglucosaminyltransferase activity / nuclear pore localization / regulation of Rac protein signal transduction / protein localization to nuclear envelope / regulation of necroptotic process / nuclear lamina / negative regulation of stem cell population maintenance / protein O-linked glycosylation / NSL complex / intermediate filament / regulation of glycolytic process / RIPK1-mediated regulated necrosis / regulation of gluconeogenesis / nuclear migration / regulation of synapse assembly / Formation of WDR5-containing histone-modifying complexes / Sin3-type complex / regulation of neurotransmitter receptor localization to postsynaptic specialization membrane / positive regulation of stem cell population maintenance / phosphatidylinositol-3,4,5-trisphosphate binding / hemopoiesis / positive regulation of proteolysis / histone acetyltransferase complex / positive regulation of lipid biosynthetic process / mitophagy / negative regulation of proteasomal ubiquitin-dependent protein catabolic process / negative regulation of protein ubiquitination / positive regulation of TORC1 signaling / response to nutrient / negative regulation of cell migration / positive regulation of translation / cell projection / response to insulin / cellular response to glucose stimulus / negative regulation of transforming growth factor beta receptor signaling pathway / circadian regulation of gene expression / mitochondrial membrane / protein processing / chromatin DNA binding / structural constituent of cytoskeleton / Regulation of necroptotic cell death / UCH proteinases / nuclear envelope / heterochromatin formation / HATs acetylate histones / positive regulation of cold-induced thermogenesis / chromatin organization / nuclear membrane / apoptotic process / regulation of transcription by RNA polymerase II / positive regulation of DNA-templated transcription / glutamatergic synapse / negative regulation of transcription by RNA polymerase II / signal transduction / positive regulation of transcription by RNA polymerase II / protein-containing complex / nucleoplasm / identical protein binding / nucleus / plasma membrane / cytosol 類似検索 - 分子機能 Signal recognition particle alu RNA binding heterodimer, srp9/1 - #150 / Lamin tail domain superfamily / Lamin tail domain / Lamin Tail Domain / Lamin-tail (LTD) domain profile. / UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit / Rossmann fold - #11380 / O-GlcNAc transferase, C-terminal / Glycosyl transferase family 41 / Signal recognition particle alu RNA binding heterodimer, srp9/1 ... Signal recognition particle alu RNA binding heterodimer, srp9/1 - #150 / Lamin tail domain superfamily / Lamin tail domain / Lamin Tail Domain / Lamin-tail (LTD) domain profile. / UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit / Rossmann fold - #11380 / O-GlcNAc transferase, C-terminal / Glycosyl transferase family 41 / Signal recognition particle alu RNA binding heterodimer, srp9/1 / Intermediate filament protein, conserved site / Intermediate filament protein / Intermediate filament (IF) rod domain signature. / Intermediate filament, rod domain / Intermediate filament (IF) rod domain profile. / Intermediate filament protein / TPR repeat / Tetratricopeptide repeat / Tetratricopeptide repeat / Tetratricopeptide repeat domain / Tetratricopeptide repeat / Glycogen Phosphorylase B; / TPR repeat region circular profile. / TPR repeat profile. / Tetratricopeptide repeats / Tetratricopeptide repeat / Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat / Alpha Horseshoe / Tetratricopeptide-like helical domain superfamily / Rossmann fold / 2-Layer Sandwich / 3-Layer(aba) Sandwich / Mainly Alpha / Alpha Beta 類似検索 - ドメイン・相同性 Chem-12V / UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit / Lamin-B2 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.4 Å 詳細データ登録者 Pathak, S. / Alonso, J. / Schimpl, M. / Rafie, K. / Blair, D.E. / Borodkin, V.S. / Albarbarawi, O. / van Aalten, D.M.F. 資金援助 英国, 1件 詳細 詳細を隠す組織 認可番号 国 Wellcome Trust WT087590MA 英国
引用ジャーナル : Nat.Struct.Mol.Biol. / 年 : 2015タイトル : The active site of O-GlcNAc transferase imposes constraints on substrate sequence.著者 : Pathak, S. / Alonso, J. / Schimpl, M. / Rafie, K. / Blair, D.E. / Borodkin, V.S. / Schuttelkopf, A.W. / Albarbarawi, O. / van Aalten, D.M. 履歴 登録 2015年5月26日 登録サイト : RCSB / 処理サイト : PDBE改定 1.0 2015年8月5日 Provider : repository / タイプ : Initial release改定 1.1 2015年8月12日 Group : Database references改定 1.2 2015年9月16日 Group : Database references改定 1.3 2024年1月10日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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