登録情報 | データベース: PDB / ID: 4zjb |
---|
タイトル | Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase(FabZ) in complex with holo-ACP from Helicobacter pylori |
---|
要素 | - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ
- Acyl carrier protein
|
---|
キーワード | LYASE/BIOSYNTHETIC PROTEIN / FAS / Fatty acid biosynthesis / complex / LYASE-BIOSYNTHETIC PROTEIN complex |
---|
機能・相同性 | 機能・相同性情報
Kdo2-lipid A biosynthetic process / (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase / lipid A biosynthetic process / phosphopantetheine binding / acyl binding / acyl carrier activity / fatty acid biosynthetic process / cytoplasm / cytosol類似検索 - 分子機能 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ / Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ / FabA-like domain / Hotdog Thioesterase / Thiol Ester Dehydrase; Chain A / HotDog domain superfamily / Polyketide synthase, phosphopantetheine-binding domain / Phosphopantetheine attachment site / Acyl carrier protein (ACP) / Phosphopantetheine attachment site ...Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ / Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ / FabA-like domain / Hotdog Thioesterase / Thiol Ester Dehydrase; Chain A / HotDog domain superfamily / Polyketide synthase, phosphopantetheine-binding domain / Phosphopantetheine attachment site / Acyl carrier protein (ACP) / Phosphopantetheine attachment site / Phosphopantetheine attachment site. / Phosphopantetheine attachment site / ACP-like superfamily / Carrier protein (CP) domain profile. / Phosphopantetheine binding ACP domain / Roll / Alpha Beta類似検索 - ドメイン・相同性 CITRIC ACID / 4'-PHOSPHOPANTETHEINE / Acyl carrier protein / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ類似検索 - 構成要素 |
---|
生物種 | ![](img/tx_bacteria.gif) Helicobacter pylori (ピロリ菌) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.55 Å |
---|
データ登録者 | Zhang, L. / Zhang, L. / Shen, X. / Jiang, H. |
---|
引用 | ジャーナル: Cell Res. / 年: 2016 タイトル: Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis. 著者: Zhang, L. / Xiao, J. / Xu, J. / Fu, T. / Cao, Z. / Zhu, L. / Chen, H.Z. / Shen, X. / Jiang, H. / Zhang, L. |
---|
履歴 | 登録 | 2015年4月29日 | 登録サイト: RCSB / 処理サイト: PDBJ |
---|
改定 1.0 | 2016年11月2日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2018年2月7日 | Group: Data collection / Derived calculations / Experimental preparation カテゴリ: diffrn_source / exptl_crystal_grow / pdbx_struct_oper_list Item: _diffrn_source.pdbx_synchrotron_site / _exptl_crystal_grow.temp / _pdbx_struct_oper_list.symmetry_operation |
---|
改定 1.2 | 2018年6月20日 | Group: Data collection / Database references / カテゴリ: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
---|
改定 1.3 | 2023年11月8日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_conn Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_leaving_atom_flag |
---|
|
---|