: / mitogen-activated protein kinase kinase kinase / MAP kinase kinase kinase activity / protein autophosphorylation / protein kinase activity / protein phosphorylation / signal transduction / protein homodimerization activity / ATP binding / cytoplasm Similarity search - Function
Mitogen-activated protein (MAP) kinase kinase kinase, MLK1-4 / Variant SH3 domain / Src homology 3 domains / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3 domain / Protein tyrosine and serine/threonine kinase / Serine-threonine/tyrosine-protein kinase, catalytic domain / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 ...Mitogen-activated protein (MAP) kinase kinase kinase, MLK1-4 / Variant SH3 domain / Src homology 3 domains / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3 domain / Protein tyrosine and serine/threonine kinase / Serine-threonine/tyrosine-protein kinase, catalytic domain / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / 2-Layer Sandwich / Orthogonal Bundle / Mainly Alpha / Alpha Beta Similarity search - Domain/homology
Mass: 18.015 Da / Num. of mol.: 39 / Source method: isolated from a natural source / Formula: H2O
Nonpolymer details
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER (AGS): ALSO KNOWN AS ATPGAMMAS
Sequence details
A214G AND LOOP DELETION OF 215-229 TO REMOVE KINASE INSERT DOMAIN S303A AND T307A TO PREVENT ...A214G AND LOOP DELETION OF 215-229 TO REMOVE KINASE INSERT DOMAIN S303A AND T307A TO PREVENT ACTIVATION LOOP PHOSPHORYLATION
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Experimental details
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Experiment
Experiment
Method: X-RAY DIFFRACTION / Number of used crystals: 1
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Sample preparation
Crystal
Density Matthews: 2.37 Å3/Da / Density % sol: 47.71 % / Description: NONE
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