- PDB-4upg: X-ray structure of calcium-free human sorcin -
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基本情報
登録情報
データベース: PDB / ID: 4upg
タイトル
X-ray structure of calcium-free human sorcin
要素
SORCIN
キーワード
METAL BINDING PROTEIN / CA-BINDING PROTEIN / PENTA-EF HAND / APOPTOSIS REGULATION
機能・相同性
機能・相同性情報
regulation of relaxation of muscle / regulation of high voltage-gated calcium channel activity / regulation of cell communication by electrical coupling / regulation of striated muscle contraction / negative regulation of cardiac muscle contraction / regulation of cardiac muscle cell contraction / Sodium/Calcium exchangers / Reduction of cytosolic Ca++ levels / muscle organ development / regulation of heart contraction ...regulation of relaxation of muscle / regulation of high voltage-gated calcium channel activity / regulation of cell communication by electrical coupling / regulation of striated muscle contraction / negative regulation of cardiac muscle contraction / regulation of cardiac muscle cell contraction / Sodium/Calcium exchangers / Reduction of cytosolic Ca++ levels / muscle organ development / regulation of heart contraction / action potential / negative regulation of heart rate / regulation of cell communication by electrical coupling involved in cardiac conduction / positive regulation of insulin secretion involved in cellular response to glucose stimulus / regulation of calcium ion transport / Ion transport by P-type ATPases / calcium channel regulator activity / intracellular sequestering of iron ion / negative regulation of ryanodine-sensitive calcium-release channel activity / regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum / Ion homeostasis / T-tubule / sarcoplasmic reticulum membrane / positive regulation of release of sequestered calcium ion into cytosol / sarcoplasmic reticulum / Stimuli-sensing channels / Z disc / calcium ion transport / heart development / DNA-binding transcription factor binding / protease binding / transmembrane transporter binding / protein heterodimerization activity / signaling receptor binding / calcium ion binding / endoplasmic reticulum membrane / signal transduction / extracellular exosome / nucleoplasm / identical protein binding / membrane / cytoplasm / cytosol 類似検索 - 分子機能
解像度: 2.1→40.59 Å / Cor.coef. Fo:Fc: 0.953 / Cor.coef. Fo:Fc free: 0.939 / SU B: 3.939 / SU ML: 0.105 / 交差検証法: THROUGHOUT / ESU R: 0.184 / ESU R Free: 0.162 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD / 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS.
Rfactor
反射数
%反射
Selection details
Rfree
0.21974
673
5.1 %
RANDOM
Rwork
0.18144
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obs
0.18324
12641
99.96 %
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溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.2 Å / 溶媒モデル: MASK