登録情報 | データベース: PDB / ID: 4rl1 |
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タイトル | Structural and functional analysis of a loading acyltransferase from the avermectin modular polyketide synthase |
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要素 | Type I polyketide synthase AVES 1 |
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キーワード | TRANSFERASE / hydrolase / ferredoxin-like fold / acyltransferase |
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機能・相同性 | 機能・相同性情報
phosphopantetheine binding / antibiotic biosynthetic process / transferase activity類似検索 - 分子機能 Polyketide synthase dimerisation element domain / Polyketide synthase dimerisation element domain / : / Malonyl-CoA ACP transacylase, ACP-binding / Malonyl-Coenzyme A Acyl Carrier Protein, domain 2 / Malonyl-Coenzyme A Acyl Carrier Protein; domain 2 / Polyketide synthase dehydratase N-terminal domain / PKS_DH / Polyketide synthase, dehydratase domain / Polyketide synthase, dehydratase domain superfamily ...Polyketide synthase dimerisation element domain / Polyketide synthase dimerisation element domain / : / Malonyl-CoA ACP transacylase, ACP-binding / Malonyl-Coenzyme A Acyl Carrier Protein, domain 2 / Malonyl-Coenzyme A Acyl Carrier Protein; domain 2 / Polyketide synthase dehydratase N-terminal domain / PKS_DH / Polyketide synthase, dehydratase domain / Polyketide synthase, dehydratase domain superfamily / Polyketide synthase, ketoreductase domain / KR domain / Malonyl-CoA ACP transacylase, ACP-binding / Polyketide synthase, C-terminal extension / Ketoacyl-synthetase C-terminal extension / Acyl transferase domain superfamily / Acyl transferase / Acyl transferase domain / Acyl transferase domain in polyketide synthase (PKS) enzymes. / Acyl transferase/acyl hydrolase/lysophospholipase / Polyketide synthase, phosphopantetheine-binding domain / Phosphopantetheine attachment site / Beta-ketoacyl synthase / Beta-ketoacyl synthase, active site / Ketosynthase family 3 (KS3) active site signature. / Polyketide synthase, beta-ketoacyl synthase domain / Beta-ketoacyl synthase, N-terminal / Beta-ketoacyl synthase, C-terminal / Beta-ketoacyl synthase, N-terminal domain / Beta-ketoacyl synthase, C-terminal domain / Thiolase-like / Phosphopantetheine attachment site / Phosphopantetheine attachment site. / Phosphopantetheine attachment site / ACP-like superfamily / Carrier protein (CP) domain profile. / Phosphopantetheine binding ACP domain / Alpha-Beta Plaits / NAD(P)-binding domain superfamily / 2-Layer Sandwich / 3-Layer(aba) Sandwich / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Streptomyces avermitilis (バクテリア) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2 Å |
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データ登録者 | Wang, F. / Wang, Y. / Zheng, J. |
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引用 | ジャーナル: Acs Chem.Biol. / 年: 2015 タイトル: Structural and functional analysis of the loading acyltransferase from avermectin modular polyketide synthase. 著者: Wang, F. / Wang, Y. / Ji, J. / Zhou, Z. / Yu, J. / Zhu, H. / Su, Z. / Zhang, L. / Zheng, J. |
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履歴 | 登録 | 2014年10月15日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2015年1月28日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2015年8月26日 | Group: Database references |
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改定 1.2 | 2023年9月20日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details |
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