- PDB-4oo8: Crystal structure of Streptococcus pyogenes Cas9 in complex with ... -
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Basic information
Entry
Database: PDB / ID: 4oo8
Title
Crystal structure of Streptococcus pyogenes Cas9 in complex with guide RNA and target DNA
Components
CRISPR-associated endonuclease Cas9/Csn1
DNA (5'-D(*CP*CP*AP*GP*CP*CP*AP*AP*GP*CP*GP*CP*AP*CP*CP*TP*AP*AP*TP*TP*TP*CP*C)-3')
RNA (97-MER)
Keywords
Hydrolase/DNA/RNA / Hydrolase-DNA-RNA complex
Function / homology
Function and homology information
maintenance of CRISPR repeat elements / 3'-5' exonuclease activity / DNA endonuclease activity / defense response to virus / Hydrolases; Acting on ester bonds / DNA binding / RNA binding / metal ion binding Similarity search - Function