Entry | Database: PDB / ID: 4ol8 |
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Title | Ty3 reverse transcriptase bound to DNA/RNA |
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Components | - 5'-D(*CP*AP*TP*CP*TP*TP*CP*CP*TP*CP*TP*CP*TP*CP*TP*C)-3'
- 5'-R(*CP*UP*GP*AP*GP*AP*GP*AP*GP*AP*GP*GP*AP*AP*GP*AP*UP*G)-3'
- Reverse transcriptase/ribonuclease H
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Keywords | TRANSFERASE / HYDROLASE/RNA/DNA / Protein-DNA/RNA / reverse transcription / DNA/RNA binding / HYDROLASE-RNA-DNA complex |
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Function / homology | Function and homology information
ribonuclease H / Hydrolases; Acting on peptide bonds (peptidases); Aspartic endopeptidases / DNA integration / RNA-directed DNA polymerase / RNA-directed DNA polymerase activity / RNA-DNA hybrid ribonuclease activity / DNA recombination / DNA-directed DNA polymerase / aspartic-type endopeptidase activity / DNA-directed DNA polymerase activity ...ribonuclease H / Hydrolases; Acting on peptide bonds (peptidases); Aspartic endopeptidases / DNA integration / RNA-directed DNA polymerase / RNA-directed DNA polymerase activity / RNA-DNA hybrid ribonuclease activity / DNA recombination / DNA-directed DNA polymerase / aspartic-type endopeptidase activity / DNA-directed DNA polymerase activity / viral translational frameshifting / proteolysis / DNA binding / RNA binding / zinc ion binding / ATP binding / nucleus / cytoplasmSimilarity search - Function Integrase p58, C-terminal domain / Peptidase A2B, Ty3 transposon peptidase / Ty3 transposon peptidase / Ty3 transposon capsid-like protein / Ty3 transposon capsid-like protein / : / Integrase zinc-binding domain / Integrase zinc binding domain / Reverse transcriptase/retrotransposon-derived protein, RNase H-like domain / RNase H-like domain found in reverse transcriptase ...Integrase p58, C-terminal domain / Peptidase A2B, Ty3 transposon peptidase / Ty3 transposon peptidase / Ty3 transposon capsid-like protein / Ty3 transposon capsid-like protein / : / Integrase zinc-binding domain / Integrase zinc binding domain / Reverse transcriptase/retrotransposon-derived protein, RNase H-like domain / RNase H-like domain found in reverse transcriptase / HIV Type 1 Reverse Transcriptase, subunit A, domain 1 / HIV Type 1 Reverse Transcriptase; Chain A, domain 1 / Reverse transcriptase/Diguanylate cyclase domain / Integrase core domain / Integrase, catalytic core / Integrase catalytic domain profile. / Reverse transcriptase domain / Reverse transcriptase (RT) catalytic domain profile. / Reverse transcriptase (RNA-dependent DNA polymerase) / zinc finger / Zinc finger, CCHC-type superfamily / Zinc finger, CCHC-type / Zinc finger CCHC-type profile. / Ribonuclease H superfamily / Aspartic peptidase domain superfamily / Ribonuclease H-like superfamily / Reverse transcriptase/Diguanylate cyclase domain / Alpha-Beta Plaits / Roll / DNA/RNA polymerase superfamily / 2-Layer Sandwich / Alpha BetaSimilarity search - Domain/homology |
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Biological species | Saccharomyces cerevisiae (brewer's yeast) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / SAD / Resolution: 3.1 Å |
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Authors | Nowak, E. / Miller, J.T. / Bona, M.K. / Studnicka, J. / Szczepanowski, R.H. / Jurkowski, J. / Le Grice, S.F.J. / Nowotny, M. |
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Citation | Journal: Nat.Struct.Mol.Biol. / Year: 2014 Title: Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry. Authors: Nowak, E. / Miller, J.T. / Bona, M.K. / Studnicka, J. / Szczepanowski, R.H. / Jurkowski, J. / Le Grice, S.F. / Nowotny, M. |
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History | Deposition | Jan 23, 2014 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Mar 5, 2014 | Provider: repository / Type: Initial release |
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Revision 1.1 | Mar 12, 2014 | Group: Structure summary |
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Revision 1.2 | Apr 2, 2014 | Group: Database references |
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Revision 1.3 | Apr 16, 2014 | Group: Database references |
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