Entry | Database: PDB / ID: 4ol8 |
---|
Title | Ty3 reverse transcriptase bound to DNA/RNA |
---|
Components | - 5'-D(*CP*AP*TP*CP*TP*TP*CP*CP*TP*CP*TP*CP*TP*CP*TP*C)-3'
- 5'-R(*CP*UP*GP*AP*GP*AP*GP*AP*GP*AP*GP*GP*AP*AP*GP*AP*UP*G)-3'
- Reverse transcriptase/ribonuclease H
|
---|
Keywords | TRANSFERASE / HYDROLASE/RNA/DNA / Protein-DNA/RNA / reverse transcription / DNA/RNA binding / HYDROLASE-RNA-DNA complex |
---|
Function / homology | Function and homology information
retrotransposon nucleocapsid / retrotransposition / Hydrolases; Acting on peptide bonds (peptidases); Aspartic endopeptidases / ribonuclease H / RNA nuclease activity / DNA integration / RNA-directed DNA polymerase / RNA-directed DNA polymerase activity / RNA-DNA hybrid ribonuclease activity / peptidase activity ...retrotransposon nucleocapsid / retrotransposition / Hydrolases; Acting on peptide bonds (peptidases); Aspartic endopeptidases / ribonuclease H / RNA nuclease activity / DNA integration / RNA-directed DNA polymerase / RNA-directed DNA polymerase activity / RNA-DNA hybrid ribonuclease activity / peptidase activity / aspartic-type endopeptidase activity / DNA recombination / DNA-directed DNA polymerase / DNA-directed DNA polymerase activity / proteolysis / DNA binding / RNA binding / zinc ion binding / ATP binding / nucleus / cytoplasmSimilarity search - Function Peptidase A2B, Ty3 transposon peptidase / Ty3 transposon peptidase / Ty3 transposon capsid-like protein / Ty3 transposon capsid-like protein / Integrase zinc-binding domain / Integrase zinc binding domain / Reverse transcriptase/retrotransposon-derived protein, RNase H-like domain / RNase H-like domain found in reverse transcriptase / HIV Type 1 Reverse Transcriptase, subunit A, domain 1 / HIV Type 1 Reverse Transcriptase; Chain A, domain 1 ...Peptidase A2B, Ty3 transposon peptidase / Ty3 transposon peptidase / Ty3 transposon capsid-like protein / Ty3 transposon capsid-like protein / Integrase zinc-binding domain / Integrase zinc binding domain / Reverse transcriptase/retrotransposon-derived protein, RNase H-like domain / RNase H-like domain found in reverse transcriptase / HIV Type 1 Reverse Transcriptase, subunit A, domain 1 / HIV Type 1 Reverse Transcriptase; Chain A, domain 1 / Reverse transcriptase/Diguanylate cyclase domain / Integrase core domain / Integrase, catalytic core / Integrase catalytic domain profile. / Reverse transcriptase (RNA-dependent DNA polymerase) / Reverse transcriptase domain / Reverse transcriptase (RT) catalytic domain profile. / zinc finger / Zinc finger, CCHC-type superfamily / Zinc finger, CCHC-type / Zinc finger CCHC-type profile. / Aspartic peptidase domain superfamily / Ribonuclease H superfamily / Ribonuclease H-like superfamily / Reverse transcriptase/Diguanylate cyclase domain / Alpha-Beta Plaits / Roll / DNA/RNA polymerase superfamily / 2-Layer Sandwich / Alpha BetaSimilarity search - Domain/homology |
---|
Biological species | Saccharomyces cerevisiae (brewer's yeast) |
---|
Method | X-RAY DIFFRACTION / SYNCHROTRON / SAD / Resolution: 3.1 Å |
---|
Authors | Nowak, E. / Miller, J.T. / Bona, M.K. / Studnicka, J. / Szczepanowski, R.H. / Jurkowski, J. / Le Grice, S.F.J. / Nowotny, M. |
---|
Citation | Journal: Nat.Struct.Mol.Biol. / Year: 2014 Title: Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry. Authors: Nowak, E. / Miller, J.T. / Bona, M.K. / Studnicka, J. / Szczepanowski, R.H. / Jurkowski, J. / Le Grice, S.F. / Nowotny, M. |
---|
History | Deposition | Jan 23, 2014 | Deposition site: RCSB / Processing site: RCSB |
---|
Revision 1.0 | Mar 5, 2014 | Provider: repository / Type: Initial release |
---|
Revision 1.1 | Mar 12, 2014 | Group: Structure summary |
---|
Revision 1.2 | Apr 2, 2014 | Group: Database references |
---|
Revision 1.3 | Apr 16, 2014 | Group: Database references |
---|
|
---|